NECAT Beamline

The Northeastern Collaborative Access Team (NE-CAT) facility at the Advanced Photon Source at Argonne National Laboratory is managed by Cornell University and consists of seven member institutions:

  • Columbia University
  • Cornell University
  • Harvard University
  • Memorial Sloan-Kettering Cancer Center
  • Massachusetts Institute of Technology
  • Rockefeller University
  • Yale University.

    Primary funding for this project comes from the National Institute of General Medical Sciences (NIGMS) , a division of the National Institutes of Health (NIH). Additional financial support for NE-CAT comes from the member institutions.

    NIGMS at a Glance.

    Supported by:

    National Institutes of Health
    National Institute of General Medical Sciences

    HKL-2000 - program suite for oscillation data processing

    The HKL-2000 suite of programs is designed to analyze X-ray diffraction data collected from single crystals. The programs have been written by Dr. Zbyszek Otwinowski (Southwestern Medical Center, University of Texas) and Dr. Wladek Minor (University of Virginia). The suite of programs on the NE-CAT beamlines are provided on the basis of scientific collaboration. The HKL-2000  package development is supported by the NIH grant GM-53163 to the laboratories of Professors Otwinowski and Minor.

    Programs included in the HKL-2000 suite

    DENZO_3D - Auto-indexing, refinement and integration
    XDISPLAYF - Image display and measurement
    SCALEPACK - Data scaling
    STRAT - Strategy and simulation
    HKLINT - Graphical Command Center


    The use of the software package should be referenced in publication as follows:
    Z. Otwinowski and W. Minor "Processing of X-ray Diffraction Data Collected in Oscillation Mode", Methods in Enzymology, Volume 276: Macromolecular Crystallography, part A, p. 307-326, 1997, C.W. Carter, Jr. and R.M. Sweet, Eds., Academic Press.

    User Information

    Experimenters who perform non-commercial research may freely use the program for data evaluation and processing while collecting data at the beamline. These experimenters can also obtain a temporary, free of charge, license to (re)process data collected at synchrotron beamlines. This license can be obtained by contacting HKL Research, Inc. Additional infortion about the HKL-2000 package may also be found at that site.

    Our agreement to use this software package does not apply to commercial research. To obtain a commercial HKL license, please see: