NECAT Beamline

The Northeastern Collaborative Access Team (NE-CAT) facility at the Advanced Photon Source at Argonne National Laboratory is managed by Cornell University and consists of seven member institutions:

  • Columbia University
  • Cornell University
  • Harvard University
  • Memorial Sloan-Kettering Cancer Center
  • Massachusetts Institute of Technology
  • Rockefeller University
  • Yale University.
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    Primary funding for this project comes from the National Institute of General Medical Sciences (NIGMS) , a division of the National Institutes of Health (NIH). Additional financial support for NE-CAT comes from the member institutions.

    NIGMS at a Glance.

    Supported by:

    National Institutes of Health
    National Institute of General Medical Sciences

    Technical Specifications for Sector 24 Beamlines   

    24-ID-C beamline:

    • Uses the out-board-projecting up-stream undulator
    • Energy range between 6 – 21 keV.
    • A focused beam of approximately 1.5x1013 Photons/Sec
    • A focal spot size variable down to 23 µm horizonal X 5 µm vertically.
    • Beam has an energy bandwidth of ΔE/E ~1 x 10-4 at an energy of ~12.66 keV at one sigma.
    • Beam stable to a few microns.
    • Beam line control system, "CONSOLE" developed by NE-CAT.
    • Remote access through a NE-CAT developed web based user interface.
    • Fast monochromatic rotary beam shutters with opening and closing times less than 5 msec, synchronized precisely with the motion state of the crystallographic spindle.
    • MD2 diffractometer, with sphere of confusion of less than 3µ (less than 7µ with mini-kappa mounted). MD2 beam shaping system provides very clean beams from 5 microns to 100 microns in diameter and has exceptional sample visualization systems capable of visualizing micron-sized crystals with extreme clarity. Optional mini-kappa, MK3, available on demand.
    • Modified ALS style sample automounter with a capacity of fourteen pucks.
    • Oxford Cryo-Jet crystal cryocoolers. (100K to 300K)
    • Amptek Silicon Drift Diode detectors for emission line scans and rapid identification of metals in crystalline or non-crystalline samples.
    • Dectris Pilatus 6MF pixel array detector.  Detector can be lifted up to four modules. Maximum crystal-to-detector distance is 1200 mm and minimum is 150 mm. Shutter-less data collection and noiseless readouts improve the data quality significantly.

     

    24-ID-E beamline:

    • Uses the inboard-projecting down-stream undulator
    • A fixed energy at 12.66 keV, with a fixed take-off angle (2Θ) of 29.5o.
    • A focused beam of approximately 1x1013 Photons/Sec
    • A focal spot size 35 µm horizontal by 5 µm vertical.
    • A beam with an energy bandwidth of ΔE/E <2 x 10-4 at an energy of ~12.66 keV at one sigma.
    • A beam that is stable to 1-2 microns.
    • MD2 diffractometer, with sphere of confusion of less than 3µ (less than 7µ with mini-kappa mounted). MD2 beam shaping system provides very clean beams from 5 microns to 100 microns in diameter and has exceptional sample visualization systems capable of visualizing micron-sized crystals with extreme clarity.
    • Modified ALS style sample automounter with a capacity of fourteen pucks.
    • Oxford Cryo-Jet crystal cryocoolers. (100K to 300K).
    • Amptek Silicon Drift Diode detectors for rapid identification of metals in crystalline or non-crystalline samples.
    • Eiger-16M pixel array detector with detector lift. Maximum crystal-to-detector distance is 1200 mm and minimum is 150 mm.

     

    Facilities shared between both beamlines:

    • Data storage: Current network storage system consists of Nexan SAN systems with an aggregate of 480 TB of available storage space over fiber-optic network, using IBM developed GPFS file system.
    • Computational Software: Essential crystallographic software is made available to users via SBGrid suite.
    • Automated data collection strategy and data processing is offered using a NE-CAT developed RAPD pipeline running on a compute cluster.
    • Computing cluster: a multi-core compute-cluster enable susers to assay data quality and evaluate the efficacy of data collection strategies on the same time scale as data collection itself.
    • A humidity-controlling device – HC1 is available to test the possibility of improving the diffraction by a small change of relative humidity of crystals.
    • Users can ship their unfrozen crystals in a temperature controlled (from 4 to 30ºC) shipping device - iQ2, for use of HC1.
    • FTS Air-Jet crystal cooler (-40 to +100 ºC).
    • A fully equipped chemistry laboratory is available for users.
    • Several sets of robotic pucks are available for users via our “puck loaning program”.