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DNAJB8 oligomerization is mediated by an aromatic-rich motif that is dispensable for substrate activity. Structure. 32, 662-678.e8
(2024) Effects of stand-alone polar residue on membrane protein stability and structure. Biochim Biophys Acta Biomembr. 1866, 184325
(2024) Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses. Immunity. 57, 1141-1159.e11
(2024) An engineered lactate oxidase based electrochemical sensor for continuous detection of biomarker lactic acid in human sweat and serum. Heliyon. 10, e34301
(2024) Enumerative Discovery of Noncanonical Polypeptide Secondary Structures. J Am Chem Soc. 146, 25501-25512
(2024) (2024) Fragment Screening to Identify Inhibitors Targeting Ribosome Binding of Shiga Toxin 2. ACS Infect Dis. 10.1021/acsinfecdis.4c00224
(2024) (2024) How ATP and dATP Act as Molecular Switches to Regulate Enzymatic Activity in the Prototypical Bacterial Class Ia Ribonucleotide Reductase. Biochemistry. 63, 2517-2531
(2024) Identification and biophysical characterization of a novel domain-swapped camelid antibody specific for fentanyl. J Biol Chem. 300, 107502
(2024) Identification and structural characterization of small molecule inhibitors of PINK1. Sci Rep. 14, 7739
(2024) Identification of the Thermal Activation Network in Human 15-Lipoxygenase-2: Divergence from Plant Orthologs and Its Relationship to Hydrogen Tunneling Activation Barriers. ACS Catal. 14, 5444-5457
(2024) The immune-evasive proline-283 substitution in influenza nucleoprotein increases aggregation propensity without altering the native structure. Sci Adv. 10, eadl6144
(2024) (2024) A large-scale type I CBASS antiphage screen identifies the phage prohead protease as a key determinant of immune activation and evasion. Cell Host Microbe. 32, 1074-1088.e5
(2024) Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain. Nat Commun. 15, 2452
(2024) (2024) Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors. Commun Chem. 7, 38
(2024) Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms. Nat Chem Biol. 10.1038/s41589-024-01685-3
(2024) A Mitochondria-Targeting SIRT3 Inhibitor with Activity against Diffuse Large B Cell Lymphoma. J Med Chem. 67, 15428-15437
(2024) Modulating the pH dependent photophysical properties of green fluorescent protein. RSC Adv. 14, 32284-32291
(2024) Molecular and structural basis for Cγ-C bond formation by PLP-dependent enzyme Fub7.. Angew Chem Int Ed Engl. 10.1002/anie.202317161
(2024) Molecular basis of CRX/DNA recognition and stoichiometry at the Ret4 response element. Structure. 10.1016/j.str.2024.07.004
(2024) Molecular Bidents with Two Electrophilic Warheads as a New Pharmacological Modality. ACS Cent Sci. 10, 1156-1166
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