Publications

Found 30 results
Filters: Author is Taylor, Alexander B  [Clear All Filters]
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Rugel, A. R., Guzman, M. A., Taylor, A. B., Chevalier, F. D., Tarpley, R. S., McHardy, S. F., Cao, X., Holloway, S. P., Anderson, T. J. C., P Hart, J., and LoVerde, P. T. (2020) Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?. Int J Parasitol Drugs Drug Resist. 13, 8-15
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Seetharaman, S. V., Taylor, A. B., Holloway, S., and P Hart, J. (2010) Structures of mouse SOD1 and human/mouse SOD1 chimeras. Arch Biochem Biophys. 503, 183-90
Choi, J. Yong, Fuerst, R., Knapinska, A. M., Taylor, A. B., Smith, L., Cao, X., P Hart, J., Fields, G. B., and Roush, W. R. (2017) Structure-Based Design and Synthesis of Potent and Selective Matrix Metalloproteinase 13 Inhibitors. J Med Chem. 60, 5816-5825
Galaleldeen, A., Taylor, A. B., Chen, D., Schuermann, J. P., Holloway, S. P., Hou, S., Gong, S., Zhong, G., and P Hart, J. (2013) Structure of the Chlamydia trachomatis immunodominant antigen Pgp3. J Biol Chem. 288, 22068-79
Becker, A., Kannan, T. R., Taylor, A. B., Pakhomova, O. N., Zhang, Y., Somarajan, S. R., Galaleldeen, A., Holloway, S. P., Baseman, J. B., and P Hart, J. (2015) Structure of CARDS toxin, a unique ADP-ribosylating and vacuolating cytotoxin from Mycoplasma pneumoniae. Proc Natl Acad Sci U S A. 112, 5165-70
Benavides, B. S., Valandro, S., Cioloboc, D., Taylor, A. B., Schanze, K. S., and Kurtz, D. M. (2020) Structure of a Zinc Porphyrin-Substituted Bacterioferritin and Photophysical Properties of Iron Reduction. Biochemistry. 59, 1618-1629
Montemayor, E. J., Katolik, A., Clark, N. E., Taylor, A. B., Schuermann, J. P., D Combs, J., Johnsson, R., Holloway, S. P., Stevens, S. W., Damha, M. J., and P Hart, J. (2014) Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1. Nucleic Acids Res. 42, 10845-55
Bhattacharya, A., Alam, S. L., Fricke, T., Zadrozny, K., Sedzicki, J., Taylor, A. B., Demeler, B., Pornillos, O., Ganser-Pornillos, B. K., Diaz-Griffero, F., Ivanov, D. N., and Yeager, M. (2014) Structural basis of HIV-1 capsid recognition by PF74 and CPSF6. Proc Natl Acad Sci U S A. 111, 18625-30
Taylor, A. B., Pica-Mattoccia, L., Polcaro, C. M., Donati, E., Cao, X., Basso, A., Guidi, A., Rugel, A. R., Holloway, S. P., Anderson, T. J. C., P Hart, J., Cioli, D., and LoVerde, P. T. (2015) Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine. PLoS Negl Trop Dis. 9, e0004132
Taylor, A. B., Roberts, K. M., Cao, X., Clark, N. E., Holloway, S. P., Donati, E., Polcaro, C. M., Pica-Mattoccia, L., Tarpley, R. S., McHardy, S. F., Cioli, D., LoVerde, P. T., Fitzpatrick, P. F., and P Hart, J. (2017) Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy. J Biol Chem. 292, 11154-11164
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Yudina, Z., Roa, A., Johnson, R., Biris, N., Vieira, D. A. de Souza, Tsiperson, V., Reszka, N., Taylor, A. B., P Hart, J., Demeler, B., Diaz-Griffero, F., and Ivanov, D. N. (2015) RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin.. Cell Rep. 12, 788-97
LoVerde, P. T., Alwan, S. N., Taylor, A. B., Rhodes, J., Chevalier, F. D., Anderson, T. Jc, and McHardy, S. F. (2021) Rational approach to drug discovery for human schistosomiasis. Int J Parasitol Drugs Drug Resist. 16, 140-147
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Sea, K. W., Taylor, A. B., Thomas, S. T., Liba, A., Bergman, I. B., Holloway, S. P., Cao, X., Gralla, E. B., Valentine, J. S., P Hart, J., and Galaleldeen, A. (2021) A pH Switch Controls Zinc Binding in Tomato Copper-Zinc Superoxide Dismutase. Biochemistry. 60, 1597-1608
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Alwan, S. N., Taylor, A. B., Rhodes, J., Tidwell, M., McHardy, S. F., and LoVerde, P. T. (2023) Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis. PLoS Pathog. 19, e1011018
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Yu, C. H., Bhattacharya, A., Persaud, M., Taylor, A. B., Wang, Z., Bulnes-Ramos, A., Xu, J., Selyutina, A., Martinez-Lopez, A., Cano, K., Demeler, B., Kim, B., Hardies, S. C., Diaz-Griffero, F., and Ivanov, D. N. (2021) Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification. Nat Commun. 12, 731
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Archer, C. R., Enslow, B. T., Taylor, A. B., De la Rosa, V., Bhattacharya, A., and Shapiro, M. S. (2019) A mutually-induced conformational fit underlies Ca-directed interactions between calmodulin and the proximal C terminus of KCNQ4 K channels. J Biol Chem. 10.1074/jbc.RA118.006857
Chinai, J. M., Taylor, A. B., Ryno, L. M., Hargreaves, N. D., Morris, C. A., P Hart, J., and Urbach, A. R. (2011) Molecular recognition of insulin by a synthetic receptor. J Am Chem Soc. 133, 8810-3
Guzman, M., Rugel, A., Tarpley, R. S., Cao, X., McHardy, S. F., LoVerde, P. T., and Taylor, A. B. (2020) Molecular basis for hycanthone drug action in schistosome parasites. Mol Biochem Parasitol. 236, 111257
Clark, N. E., Katolik, A., Roberts, K. M., Taylor, A. B., Holloway, S. P., Schuermann, J. P., Montemayor, E. J., Stevens, S. W., Fitzpatrick, P. F., Damha, M. J., and P Hart, J. (2016) Metal dependence and branched RNA cocrystal structures of the RNA lariat debranching enzyme Dbr1. Proc Natl Acad Sci U S A. 113, 14727-14732
Adachi, M. S., Taylor, A. B., P Hart, J., and Fitzpatrick, P. F. (2012) Mechanistic and structural analyses of the roles of active site residues in yeast polyamine oxidase Fms1: characterization of the N195A and D94N enzymes. Biochemistry. 51, 8690-7
Adachi, M. S., Taylor, A. B., P Hart, J., and Fitzpatrick, P. F. (2012) Mechanistic and structural analyses of the role of His67 in the yeast polyamine oxidase Fms1. Biochemistry. 51, 4888-97
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Wong, S. J., Gearhart, M. D., Taylor, A. B., Nanyes, D. R., Ha, D. J., Robinson, A. K., Artigas, J. A., Lee, O. J., Demeler, B., P Hart, J., Bardwell, V. J., and Kim, C. A. (2016) KDM2B Recruitment of the Polycomb Group Complex, PRC1.1, Requires Cooperation between PCGF1 and BCORL1. Structure. 24, 1795-1801
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Tormos, J. R., Taylor, A. B., S Daubner, C., P Hart, J., and Fitzpatrick, P. F. (2010) Identification of a hypothetical protein from Podospora anserina as a nitroalkane oxidase. Biochemistry. 49, 5035-41
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Kim, S. Kyung, Barron, L., Hinck, C. S., Petrunak, E. M., Cano, K. E., Thangirala, A., Iskra, B., Brothers, M., Vonberg, M., Leal, B., Richter, B., Kodali, R., Taylor, A. B., Du, S., Barnes, C. O., Sulea, T., Calero, G., P Hart, J., Hart, M. J., Demeler, B., and Hinck, A. P. (2017) An engineered transforming growth factor β (TGF-β) monomer that functions as a dominant negative to block TGF-β signaling.. J Biol Chem. 292, 7173-7188
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Meisburger, S. P., Taylor, A. B., Khan, C. A., Zhang, S., Fitzpatrick, P. F., and Ando, N. (2016) Domain Movements upon Activation of Phenylalanine Hydroxylase Characterized by Crystallography and Chromatography-Coupled Small-Angle X-ray Scattering. J Am Chem Soc. 138, 6506-16

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