Publications
Found 179 results
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Macrocyclization of Quinazoline-Based EGFR Inhibitors Leads to Exclusive Mutant Selectivity for EGFR L858R and Del19. J Med Chem. 65, 15679-15697
(2022) Macrolide-peptide conjugates as probes of the path of travel of the nascent peptides through the ribosome. ACS Chem Biol. 9, 2621-31
(2014) Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms. Nat Chem Biol. 10.1038/s41589-024-01685-3
(2024) The macular degeneration-linked C1QTNF5 (S163) mutation causes higher-order structural rearrangements. J Struct Biol. 186, 86-94
(2014) Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state. Nucleic Acids Res. 10.1093/nar/gkx413
(2017) Mammalian Nudix proteins cleave nucleotide metabolite caps on RNAs. Nucleic Acids Res. 10.1093/nar/gkaa402
(2020) Manganese binding properties of human calprotectin under conditions of high and low calcium: X-ray crystallographic and advanced electron paramagnetic resonance spectroscopic analysis. J Am Chem Soc. 137, 3004-16
(2015) (2013) (2017) The Mathematical Lens - Fourier Transform. University of Burdwan
(2021) The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer. Nat Chem Biol. 6, 595-601
(2010) Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes. Protein Sci. 19, 507-19
(2010) Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid. Nat Commun. 10, 5256
(2019) A Mechanically Weak Extracellular Membrane-Adjacent Domain Induces Dimerization of Protocadherin-15. Biophys J. 115, 2368-2385
(2018) Mechanism and Structure of the Cdc48 ATPase Complex. Ph.D. thesis, Harvard University, Cambridge, Massachusetts
(2018) Mechanism for activation of mutated epidermal growth factor receptors in lung cancer. Proc Natl Acad Sci U S A. 110, E3595-604
(2013) Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure. 16, 1678-88
(2008) Mechanism for KRIT1 release of ICAP1-mediated suppression of integrin activation. Mol Cell. 49, 719-29
(2013) Mechanism of a cytosolic O-glycosyltransferase essential for the synthesis of a bacterial adhesion protein. Proc Natl Acad Sci U S A. 113, E1190-9
(2016) Mechanism of activation gating in the full-length KcsA K+ channel. Proc Natl Acad Sci U S A. 108, 11896-9
(2011) (2013) (2016) Mechanism of Cd2+ coordination during slow inactivation in potassium channels. Structure. 20, 1332-42
(2012) (2016) Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge. J Exp Med. 10.1084/jem.20191792
(2020)