Publications

Found 187 results
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2024
Aleksandrova, E. V., Ma, C. - X., Klepacki, D., Alizadeh, F., Vázquez-Laslop, N., Liang, J. - H., Polikanov, Y. S., and Mankin, A. S. (2024) Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms. Nat Chem Biol. 10.1038/s41589-024-01685-3
Barnes, C. L., Salom, D., Namitz, K. E. W., W Smith, C., Knutson, B. A., Cosgrove, M. S., Kiser, P. D., and Calvert, P. D. (2024) Mechanisms of amphibian arrestin 1 self-association and dynamic distribution in retinal photoreceptors. J Biol Chem. 300, 107966
Torrens-Spence, M. P., Matos, J. O., Li, T., Kastner, D. W., Kim, C. Y., Wang, Z., Glinkerman, C. M., Sherk, J., Kulik, H. J., Wang, Y., and Weng, J. - K. (2024) Mechanistic basis for the emergence of EPS1 as a catalyst in salicylic acid biosynthesis of Brassicaceae. Nat Commun. 15, 10356
Jana, S., Shang, J., Hong, J. Young, Fenwick, M. K., Puri, R., Lu, X., Melnick, A. M., Li, M., and Lin, H. (2024) A Mitochondria-Targeting SIRT3 Inhibitor with Activity against Diffuse Large B Cell Lymphoma. J Med Chem. 67, 15428-15437
Broughton, D. P., Holod, C. G., Camilo-Contreras, A., Harris, D. R., Brewer, S. H., and Phillips-Piro, C. M. (2024) Modulating the pH dependent photophysical properties of green fluorescent protein. RSC Adv. 14, 32284-32291
Liu, S., Yeh, C., Reavill, C., Jones, B., Zou, Y., and Hai, Y. (2024) Molecular and structural basis for Cγ-C bond formation by PLP-dependent enzyme Fub7.. Angew Chem Int Ed Engl. 10.1002/anie.202317161
Srivastava, D., Gowribidanur-Chinnaswamy, P., Gaur, P., Spies, M., Swaroop, A., and Artemyev, N. O. (2024) Molecular basis of CRX/DNA recognition and stoichiometry at the Ret4 response element. Structure. 10.1016/j.str.2024.07.004
Anderson, M. J. M., Hayward, A. N., Smiley, A. T., Shi, K., Pawlak, M. R., Aird, E. J., Grant, E., Greenberg, L., Aihara, H., Evans, R. L., Ulens, C., and Gordon, W. R. (2024) Molecular basis of proteolytic cleavage regulation by the extracellular matrix receptor dystroglycan. Structure. 32, 1984-1996.e5
Li, Z., Jiang, J., Ficarro, S. B., Beyett, T. S., To, C., Tavares, I., Zhu, Y., Li, J., Eck, M. J., Jänne, P. A., Marto, J. A., Zhang, T., Che, J., and Gray, N. S. (2024) Molecular Bidents with Two Electrophilic Warheads as a New Pharmacological Modality. ACS Cent Sci. 10, 1156-1166
2022
Amrhein, J. A., Beyett, T. S., Feng, W. W., Krämer, A., Weckesser, J., Schaeffner, I. K., Rana, J. K., Jänne, P. A., Eck, M. J., Knapp, S., and Hanke, T. (2022) Macrocyclization of Quinazoline-Based EGFR Inhibitors Leads to Exclusive Mutant Selectivity for EGFR L858R and Del19. J Med Chem. 65, 15679-15697
Fang, J., Jiang, J., Leichter, S. M., Liu, J., Biswal, M., Khudaverdyan, N., Zhong, X., and Song, J. (2022) Mechanistic basis for maintenance of CHG DNA methylation in plants. Nat Commun. 13, 3877
Dumitrescu, D. G., Gordon, E. M., Kovalyova, Y., Seminara, A. B., Duncan-Lowey, B., Forster, E. R., Zhou, W., Booth, C. J., Shen, A., Kranzusch, P. J., and Hatzios, S. K. (2022) A microbial transporter of the dietary antioxidant ergothioneine. Cell. 185, 4526-4540.e18
Hong, Z., Adlakha, J., Wan, N., Guinn, E., Giska, F., Gupta, K., Melia, T. J., and Reinisch, K. M. (2022) Mitoguardin-2-mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation. J Cell Biol. 10.1083/jcb.202207022
Beyett, T. S., To, C., Heppner, D. E., Rana, J. K., Schmoker, A. M., Jang, J., De Clercq, D. J. H., Gomez, G., Scott, D. A., Gray, N. S., Jänne, P. A., and Eck, M. J. (2022) Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors. Nat Commun. 13, 2530
Ha, B. Hak, Yigit, S., Natarajan, N., Morse, E. M., Calderwood, D. A., and Boggon, T. J. (2022) Molecular basis for integrin adhesion receptor binding to p21-activated kinase 4 (PAK4). Commun Biol. 5, 1257

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