Publications
Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C. Biochem Pharmacol. 109, 14-26
(2016) Crystal Structures of Group B Streptococcus Glyceraldehyde-3-Phosphate Dehydrogenase: Apo-Form, Binary and Ternary Complexes. PLoS One. 11, e0165917
(2016) Ligand Binding Induces Conformational Changes in Human Cellular Retinol-binding Protein 1 (CRBP1) Revealed by Atomic Resolution Crystal Structures. J Biol Chem. 291, 8528-40
(2016) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. 2016 Annual Meeting of the American Crystallographic Association, July 22-26, 2016
(2016) nido-Dicarbaborate Induces Potent and Selective Inhibition of Cyclooxygenase-2. ChemMedChem. 11, 175-8
(2016) Poxvirus uracil-DNA glycosylase-An unusual member of the family I uracil-DNA glycosylases. Protein Sci. 25, 2113-2131
(2016) Structural Insights into the Drosophila melanogaster Retinol Dehydrogenase, a Member of the Short-Chain Dehydrogenase/Reductase Family. Biochemistry. 55, 6545-6557
(2016) (2016) (2016) Challenging Structural Biology Research at NE-CAT. BES Trienniel Review of the APS, August 15, 2017
(2017) Enzyme That Makes You Cry-Crystal Structure of Lachrymatory Factor Synthase from Allium cepa. ACS Chem Biol. 10.1021/acschembio.7b00336
(2017) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. Award Winners and Abstracts of the 31st Annual Symposium of The Protein Society, Montreal, Canada, July 24-27, 2017. 26, 6-209
(2017) Northeastern Collaborative Access Team (NE-CAT) Crystallography Beam Lines for Challenging Structural Biology Research. 2017 Annual Meeting of the American Crystallographic Association, May 26-30, 2017
(2017) Photocyclic behavior of rhodopsin induced by an atypical isomerization mechanism. Proc Natl Acad Sci U S A. 114, E2608-E2615
(2017) Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B. Nat Struct Mol Biol. 24, 131-139
(2017) Structure and Spectroscopy of Alkene-Cleaving Dioxygenases Containing an Atypically Coordinated Non-Heme Iron Center. Biochemistry. 56, 2836-2852
(2017) The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism. Mol Cell. 69, 75-86.e9
(2018) The Critical Tools Needed To Deal with Challenging Structural Biology Projects. Chemistry Colloquium, Shiv Nadar University
(2018) (2018) Dual cyclooxygenase-fatty acid amide hydrolase inhibitor exploits novel binding interactions in the cyclooxygenase active site. J Biol Chem. 10.1074/jbc.M117.802058
(2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. Biophysical Society 62nd Annual Meeting, Feb 17-21, 2018
(2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. Award Winners and Abstracts of the 32nd Annual Symposium of The Protein Society; Boston, MA, July 9-12, 2018. 27 Suppl 1, 11-245
(2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. COMPPÅ Symposium on Membrane Protein Production and Analysis, June 17-19, 2018
(2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. 2018 Annual Meeting of the American Crystallographic Association, July 20-24, 2018
(2018) Northeastern Collaborative Access Team (NE-CAT) crystallography beamlines for challenging structural biology research. Acta Crystallographica Section A Foundations and Advances. 74, a97-a97
(2018)