Publications

Found 19 results
Filters: Author is Dunham, Christine M  [Clear All Filters]
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Pierson, W. E., Hoffer, E. D., Keedy, H. E., Simms, C. L., Dunham, C. M., and Zaher, H. S. (2016) Uniformity of Peptide Release Is Maintained by Methylation of Release Factors. Cell Rep. 17, 11-8
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Schureck, M. A., Maehigashi, T., Miles, S. J., Marquez, J., Cho, S. Ei, Erdman, R., and Dunham, C. M. (2014) Structure of the Proteus vulgaris HigB-(HigA)2-HigB toxin-antitoxin complex. J Biol Chem. 289, 1060-70
Meisner, J., Maehigashi, T., André, I., Dunham, C. M., and Moran, C. P. (2012) Structure of the basal components of a bacterial transporter. Proc Natl Acad Sci U S A. 109, 5446-51
Hoffer, E. D., Miles, S. J., and Dunham, C. M. (2017) The structure and function of Mycobacterium tuberculosis MazF-mt6 toxin provide insights into conserved features of MazF endonucleases. J Biol Chem. 292, 7718-7726
Fagan, C. E., Maehigashi, T., Dunkle, J. A., Miles, S. J., and Dunham, C. M. (2014) Structural insights into translational recoding by frameshift suppressor tRNASufJ. RNA. 20, 1944-54
Rivera, S., Young, P. G., Hoffer, E. D., Vansuch, G. E., Metzler, C. L., Dunham, C. M., and Weinert, E. E. (2018) Structural Insights into Oxygen-Dependent Signal Transduction within Globin Coupled Sensors. Inorg Chem. 57, 14386-14395
Hoffer, E., Hong, S., Sunita, S., Maehigashi, T., Gonzalez, R. L., Whitford, P., and Dunham, C. M. (2020) Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing. Elife. 10.7554/eLife.51898
Maehigashi, T., Dunkle, J. A., Miles, S. J., and Dunham, C. M. (2014) Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc Natl Acad Sci U S A. 111, 12740-5
Schureck, M. A., Meisner, J., Hoffer, E. D., Wang, D., Onuoha, N., Cho, S. Ei, Lollar, P., and Dunham, C. M. (2019) Structural basis of transcriptional regulation by the HigA antitoxin. Mol Microbiol. 10.1111/mmi.14229
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Hoffer, E. D., Maehigashi, T., Fredrick, K., and Dunham, C. M. (2018) Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.. Nucleic Acids Res. 10.1093/nar/gky1178
Fagan, C. E., Dunkle, J. A., Maehigashi, T., Dang, M. N., Devaraj, A., Miles, S. J., Qin, D., Fredrick, K., and Dunham, C. M. (2013) Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state. Proc Natl Acad Sci U S A. 110, 9716-21
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Pavelich, I. J., Maehigashi, T., Hoffer, E. D., Ruangprasert, A., Miles, S. J., and Dunham, C. M. (2019) Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability. Nucleic Acids Res. 10.1093/nar/gkz760
Dunkle, J. A., Vinal, K., Desai, P. M., Zelinskaya, N., Savic, M., West, D. M., Conn, G. L., and Dunham, C. M. (2014) Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA. Proc Natl Acad Sci U S A. 111, 6275-80
Ruangprasert, A., Maehigashi, T., Miles, S. J., Giridharan, N., Liu, J. X., and Dunham, C. M. (2014) Mechanisms of toxin inhibition and transcriptional repression by Escherichia coli DinJ-YafQ. J Biol Chem. 289, 20559-69
Hong, S., Sunita, S., Maehigashi, T., Hoffer, E. D., Dunkle, J. A., and Dunham, C. M. (2018) Mechanism of tRNA-mediated +1 ribosomal frameshifting. Proc Natl Acad Sci U S A. 10.1073/pnas.1809319115
Washington, A. Z., Benicewicz, D. B., Canzoneri, J. C., Fagan, C. E., Mwakwari, S. C., Maehigashi, T., Dunham, C. M., and Oyelere, A. K. (2014) Macrolide-peptide conjugates as probes of the path of travel of the nascent peptides through the ribosome. ACS Chem Biol. 9, 2621-31
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Nguyen, H. An, Hoffer, E. D., and Dunham, C. M. (2019) Importance of tRNA anticodon loop modification and a conserved, noncanonical anticodon stem pairing in tRNA for decoding. J Biol Chem. 10.1074/jbc.RA119.007410
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Nguyen, H. An, Sunita, S., and Dunham, C. M. (2020) Disruption of evolutionarily correlated tRNA elements impairs accurate decoding. Proc Natl Acad Sci U S A. 117, 16333-16338
Schureck, M. A., Dunkle, J. A., Maehigashi, T., Miles, S. J., and Dunham, C. M. (2015) Defining the mRNA recognition signature of a bacterial toxin protein. Proc Natl Acad Sci U S A. 112, 13862-7