Publications
(2018) Northeastern Collaborative Access Team (NE-CAT) crystallography beamlines for challenging structural biology research. Acta Crystallographica Section A Foundations and Advances. 74, a97-a97
(2018) Structural and biochemical characterization of the protease domain of the mosaic botulinum neurotoxin type HA. Pathog Dis. 10.1093/femspd/fty044
(2018) A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1. Nat Commun. 9, 5367
(2017) A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding. Sci Rep. 7, 7438
(2017) Challenging Structural Biology Research at NE-CAT. BES Trienniel Review of the APS, August 15, 2017
(2017) Crystal Structure of the Receptor-Binding Domain of Botulinum Neurotoxin Type HA, Also Known as Type FA or H. Toxins (Basel). 10.3390/toxins9030093
(2017) The hypothetical protein P47 of Clostridium botulinum E1 strain Beluga has a structural topology similar to bactericidal/permeability-increasing protein. Toxicon. 10.1016/j.toxicon.2017.10.012
(2017) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. Award Winners and Abstracts of the 31st Annual Symposium of The Protein Society, Montreal, Canada, July 24-27, 2017. 26, 6-209
(2017) Northeastern Collaborative Access Team (NE-CAT) Crystallography Beam Lines for Challenging Structural Biology Research. 2017 Annual Meeting of the American Crystallographic Association, May 26-30, 2017
(2016) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. 2016 Annual Meeting of the American Crystallographic Association, July 22-26, 2016
(2016) N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A. Nat Struct Mol Biol. 23, 656-62
(2016) Structure of 'linkerless' hydroxamic acid inhibitor-HDAC8 complex confirms the formation of an isoform-specific subpocket. J Struct Biol. 195, 373-378
(2015) Exploration of Monosaccharide Inhibitors for Trypanosoma cruzi Glucokinase and Hexokinase. 66th Southeastern Regional Meeting of the American Chemical Society, October 16-19, 2015
(2015) Identification of Non-nucleoside Human Ribonucleotide Reductase Modulators. J Med Chem. 58, 9498-509
(2015) Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics. Toxicon. 107, 43-9
(2015) Structure-based approach to the identification of a novel group of selective glucosamine analogue inhibitors of Trypanosoma cruzi glucokinase. Mol Biochem Parasitol. 204, 64-76
(2014) High-resolution crystal structure of HA33 of botulinum neurotoxin type B progenitor toxin complex. Biochem Biophys Res Commun. 446, 568-73
(2014) Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex. Science. 344, 1405-10
(2014) NE-CAT Crystallography Beamlines for Challenging Structural Biology Research. 23rd International Union of Crystallography (IuCr) and General Assembly, August 5-12, 2014
(2014) Structure determination of BA0150, a putative polysaccharide deacetylase from Bacillus anthracis. Acta Crystallogr F Struct Biol Commun. 70, 156-9
(2014) Structures of bacterial homologues of SWEET transporters in two distinct conformations. Nature. 515, 448-52