Publications
Found 100 results
Filters: Author is Sawaya, Michael R [Clear All Filters]
The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex from M. tuberculosis reveals a Mg²⁺ ion in the active site and a putative RNA-binding site.. Protein Sci. 21, 1754-67
(2012) Crystal Structure of the Streptomyces coelicolor Sortase E1 Transpeptidase Provides Insight into the Binding Mode of the Novel Class E Sorting Signal. PLoS One. 11, e0167763
(2016) Crystal Structures of Amyloidogenic Segments of Human Transthyretin. Protein Sci. 10.1002/pro.3420
(2018) Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets. J Phys Chem B. 120, 5810-6
(2016) Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci. 19, 1031-43
(2010) Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease. J Biol Chem. 285, 29671-5
(2010) The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril.. Science. 355, 831-833
(2017) Determination of the X-ray structure of the snake venom protein omwaprin by total chemical synthesis and racemic protein crystallography. Protein Sci. 19, 1840-9
(2010) Directed evolution and structural characterization of a simvastatin synthase. Chem Biol. 16, 1064-74
(2009) Distal Amyloid β-Protein Fragments Template Amyloid Assembly.. Protein Sci. 10.1002/pro.3375
(2018) DNAJB8 oligomerization is mediated by an aromatic-rich motif that is dispensable for substrate activity. Structure. 32, 662-678.e8
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Geometric Lessons and Design Strategies for Nanoscale Protein Cages. ACS Nano. 10.1021/acsnano.0c07167
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Identification of a unique Fe-S cluster binding site in a glycyl-radical type microcompartment shell protein. J Mol Biol. 426, 3287-304
(2014) Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light chain amyloidosis. J Biol Chem. 10.1074/jbc.RA118.004142
(2018) Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies. Nat Struct Mol Biol. 29, 529-536
(2022) Inhibiting amyloid-β cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design.. Nat Chem. 10.1038/s41557-018-0147-z
(2018) Inhibition by small-molecule ligands of formation of amyloid fibrils of an immunoglobulin light chain variable domain. Elife. 4, e10935
(2015) Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2. bioRxiv. 10.1101/2021.03.05.434000
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