Publications
Found 116 results
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(2017) Intramolecular autoinhibition of checkpoint kinase 1 is mediated by conserved basic motifs of the C-terminal kinase-associated 1 domain. J Biol Chem. 292, 19024-19033
(2023) Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity. Proc Natl Acad Sci U S A. 120, e2222073120
(2021) Identification of gp120 Residue His105 as a Novel Target for HIV-1 Neutralization by Small-Molecule CD4-Mimics. ACS Med Chem Lett. 12, 1824-1831
(2024) Identification and biophysical characterization of a novel domain-swapped camelid antibody specific for fentanyl. J Biol Chem. 300, 107502
(2023) Inhibition of talin-induced integrin activation by a double-hit stapled peptide. Structure. 31, 948-957.e3
(2023) Immunodominant surface epitopes power immune evasion in the African trypanosome. Cell Rep. 42, 112262
(2016) Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1-F-box interface. Proc Natl Acad Sci U S A. 113, 3527-32
(2012) Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin.. Proc Natl Acad Sci U S A. 109, 17942-7
(2018) Isonitrile Formation by a Non-Heme Iron(II)-Dependent Oxidase/Decarboxylase. Angew Chem Int Ed Engl. 57, 9707-9710
(2020) Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering. Cell Chem Biol. 27, 647-656.e6
(2018) Improving T Cell Receptor On-Target Specificity via Structure-Guided Design. Mol Ther. 10.1016/j.ymthe.2018.12.010
(2013) An Iml3-Chl4 heterodimer links the core centromere to factors required for accurate chromosome segregation. Cell Rep. 5, 29-36
(2004) Insights into strand displacement and processivity from the crystal structure of the protein-primed DNA polymerase of bacteriophage phi29. Mol Cell. 16, 609-18
(2006) Implications of structures of synaptic tetramers of gamma delta resolvase for the mechanism of recombination. Proc Natl Acad Sci U S A. 103, 10642-7
(2013) Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization. Nat Chem Biol. 9, 428-36
(2015) Inhibition of ErbB3 by a monoclonal antibody that locks the extracellular domain in an inactive configuration. Proc Natl Acad Sci U S A. 112, 13225-30
(2015) Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics. Toxicon. 107, 43-9
(2018) Intramembrane Thiol Oxidoreductases: Evolutionary Convergence and Structural Controversy. Biochemistry. 57, 258-266
(2021) Insights into the structure and RNA-binding specificity of Caenorhabditis elegans Dicer-related helicase 3 (DRH-3). Nucleic Acids Res. 49, 9978-9991
(2013) The initiation of mammalian protein synthesis and mRNA scanning mechanism. Nature. 500, 307-11
(2021) Insight into the molecular basis of substrate recognition by the wall teichoic acid glycosyltransferase TagA. J Biol Chem. 10.1016/j.jbc.2021.101464
(2016) Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome. Nucleic Acids Res. 44, 4978-87