Publications

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T Schmeing, M., Moore, P. B., and Steitz, T. A. (2003) Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit. RNA. 9, 1345-52
Reimer, J. M., Eivaskhani, M., Harb, I., Guarné, A., Weigt, M., and T Schmeing, M. (2019) Structures of a dimodular nonribosomal peptide synthetase reveal conformational flexibility. Science. 10.1126/science.aaw4388
Sharon, I., Haque, A. S., Grogg, M., Lahiri, I., Seebach, D., Leschziner, A. E., Hilvert, D., and T Schmeing, M. (2021) Structures and function of the amino acid polymerase cyanophycin synthetase. Nat Chem Biol. 17, 1101-1110
Fortinez, C. Marie, Bloudoff, K., Harrigan, C., Sharon, I., Strauss, M., and T Schmeing, M. (2022) Structures and function of a tailoring oxidase in complex with a nonribosomal peptide synthetase module. Nat Commun. 13, 548
Sharon, I., Grogg, M., Hilvert, D., and T Schmeing, M. (2022) The structure of cyanophycinase in complex with a cyanophycin degradation intermediate. Biochim Biophys Acta Gen Subj. 1866, 130217
Patteson, J. B., Fortinez, C. Marie, Putz, A. T., Rodriguez-Rivas, J., L Bryant, H., Adhikari, K., Weigt, M., T Schmeing, M., and Li, B. (2022) Structure and Function of a Dehydrating Condensation Domain in Nonribosomal Peptide Biosynthesis. J Am Chem Soc. 144, 14057-14070
Reimer, J. M., Harb, I., Ovchinnikova, O. G., Jiang, J., Whitfield, C., and T Schmeing, M. (2018) Structural Insight into a Novel Formyltransferase and Evolution to a Nonribosomal Peptide Synthetase Tailoring Domain. ACS Chem Biol. 10.1021/acschembio.8b00739
Alonzo, D. A., Chiche-Lapierre, C., Tarry, M. J., Wang, J., and T Schmeing, M. (2020) Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis. Nat Chem Biol. 10.1038/s41589-020-0481-5