Publications
(2014) Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism. Nat Chem Biol. 10, 106-12
(2014) Recent Developments at NE-CAT, a Macromolecular Crystallography Synchrotron Facility. Indo-US International Conference/Workshop on Recent Advances in Structural Biology and Drug Discovery, October 9-11, 2014
(2014) Reprogramming the chemodiversity of terpenoid cyclization by remolding the active site contour of epi-isozizaene synthase. Biochemistry. 53, 1155-68
(2014) The role of distant mutations and allosteric regulation on LovD active site dynamics. Nat Chem Biol. 10, 431-6
(2013) RAC1P29S is a spontaneously activating cancer-associated GTPase. Proc Natl Acad Sci U S A. 110, 912-7
(2013) Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system. Nucleic Acids Res. 41, 6332-46
(2013) Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state. Proc Natl Acad Sci U S A. 110, 9716-21
(2013) Replication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymerase. Nucleic Acids Res. 41, 2060-71
(2013) On the reproducibility of protein crystal structures: five atomic resolution structures of trypsin. Acta Crystallogr D Biol Crystallogr. 69, 1447-62
(2013) Reversal of the substrate specificity of CMP N-glycosidase to dCMP. Biochemistry. 52, 4037-47
(2013) Ring-opening of the γ-OH-PdG adduct promotes error-free bypass by the Sulfolobus solfataricus DNA polymerase Dpo4.. Chem Res Toxicol. 26, 1348-60
(2013) The role of nonconserved residues of Archaeoglobus fulgidus ferritin on its unique structure and biophysical properties. J Biol Chem. 288, 32663-72
(2012) Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2. Nature. 483, 59-63
(2012) Regulation of the intersubunit ammonia tunnel in Mycobacterium tuberculosis glutamine-dependent NAD+ synthetase. Biochem J. 443, 417-26
(2012) The RGD finger of Del-1 is a unique structural feature critical for integrin binding. FASEB J. 26, 3412-20
(2012) Ribonuclease A suggests how proteins self-chaperone against amyloid fiber formation. Protein Sci. 21, 26-37
(2012) Role of arginine 293 and glutamine 288 in communication between catalytic and allosteric sites in yeast ribonucleotide reductase. J Mol Biol. 419, 315-29
(2012) RWD domain: a recurring module in kinetochore architecture shown by a Ctf19-Mcm21 complex structure. EMBO Rep. 13, 216-22
(2011) rac-6-Hy-droxy-2,5,7,8-tetra-methyl-chroman-2-carboxamide from synchrotron data. Acta Crystallogr Sect E Struct Rep Online. 67, o503-4
(2011) Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions. Cell. 145, 692-706
(2011) Recognition of the centromere-specific histone Cse4 by the chaperone Scm3. Proc Natl Acad Sci U S A. 108, 9367-71
(2011) Replacement of the axial copper ligand methionine with lysine in amicyanin converts it to a zinc-binding protein that no longer binds copper. J Inorg Biochem. 105, 1638-44
(2011) A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases. Nat Struct Mol Biol. 18, 947-9
(2011) (R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2. Nat Chem Biol. 7, 803-9