Publications

Found 181 results
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2018
Lv, Z., Yuan, L., Atkison, J. H., Williams, K. M., Vega, R., E Sessions, H., Divlianska, D. B., Davies, C., Chen, Y., and Olsen, S. K. (2018) Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme. Nat Commun. 9, 5145
Torrens-Spence, M. Patrick, Liu, C. - T., Pluskal, T., Chung, Y. Kwan, and Weng, J. - K. (2018) Monoamine Biosynthesis via a Noncanonical Calcium-Activatable Aromatic Amino Acid Decarboxylase in Psilocybin Mushroom. ACS Chem Biol. 13, 3343-3353
Chen, W., Mandali, S., Hancock, S. P., Kumar, P., Collazo, M., Cascio, D., and Johnson, R. C. (2018) Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS-family transposition. Elife. 10.7554/eLife.39611
Yu, G., Zhao, Y., and Li, H. (2018) The multistructural forms of box C/D ribonucleoprotein particles. RNA. 24, 1625-1633
2017
Osterman, I. A., Khabibullina, N. F., Komarova, E. S., Kasatsky, P., Kartsev, V. G., Bogdanov, A. A., Dontsova, O. A., Konevega, A. L., Sergiev, P. V., and Polikanov, Y. S. (2017) Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state. Nucleic Acids Res. 10.1093/nar/gkx413
Chevalier, A., Silva, D. - A., Rocklin, G. J., Hicks, D. R., Vergara, R., Murapa, P., Bernard, S. M., Zhang, L., Lam, K. - H., Yao, G., Bahl, C. D., Miyashita, S. - I., Goreshnik, I., Fuller, J. T., Koday, M. T., Jenkins, C. M., Colvin, T., Carter, L., Bohn, A., Bryan, C. M., D Fernández-Velasco, A., Stewart, L., Dong, M., Huang, X., Jin, R., Wilson, I. A., Fuller, D. H., and Baker, D. (2017) Massively parallel de novo protein design for targeted therapeutics. Nature. 550, 74-79
Yockey, O. P., Jha, V., Ghodke, P. P., Xu, T., Xu, W., Ling, H., Pradeepkumar, P. I., and Zhao, L. (2017) Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase κ.. Chem Res Toxicol. 10.1021/acs.chemrestox.7b00227
Jain, R., Choudhury, J. Roy, Buku, A., Johnson, R. E., Prakash, L., Prakash, S., and Aggarwal, A. K. (2017) Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-ι.. Sci Rep. 7, 43904
Latorraca, N. R., Fastman, N. M., Venkatakrishnan, A. J., Frommer, W. B., Dror, R. O., and Feng, L. (2017) Mechanism of Substrate Translocation in an Alternating Access Transporter. Cell. 169, 96-107.e12
Yang, H., Jiang, X., Li, B., Yang, H. J., Miller, M., Yang, A., Dhar, A., and Pavletich, N. P. (2017) Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature. 552, 368-373
Huang, H. - T., Seo, H. - S., Zhang, T., Wang, Y., Jiang, B., Li, Q., Buckley, D. L., Nabet, B., Roberts, J. M., Paulk, J., Dastjerdi, S., Winter, G. E., McLauchlan, H., Moran, J., Bradner, J. E., Eck, M. J., Dhe-Paganon, S., Zhao, J. J., and Gray, N. S. (2017) MELK is not necessary for the proliferation of basal-like breast cancer cells. Elife. 10.7554/eLife.26693
Yang, Y., Ke, N., Liu, S., and Li, W. (2017) Methods for Structural and Functional Analyses of Intramembrane Prenyltransferases in the UbiA Superfamily. Methods Enzymol. 584, 309-347
Couzens, A. L., Xiong, S., Knight, J. D. R., Mao, D. Y., Guettler, S., Picaud, S., Kurinov, I., Filippakopoulos, P., Sicheri, F., and Gingras, A. - C. (2017) MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway. Mol Cell Proteomics. 16, 1098-1110
Schmitzberger, F., Richter, M. M., Gordiyenko, Y., Robinson, C. V., Dadlez, M., and Westermann, S. (2017) Molecular basis for inner kinetochore configuration through RWD domain-peptide interactions. EMBO J. 36, 3458-3482
Wu, Y., Albrecht, T. R., Baillat, D., Wagner, E. J., and Tong, L. (2017) Molecular basis for the interaction between Integrator subunits IntS9 and IntS11 and its functional importance. Proc Natl Acad Sci U S A. 114, 4394-4399
Zhang, Y., Shan, C. - M., Wang, J., Bao, K., Tong, L., and Jia, S. (2017) Molecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation. Sci Rep. 7, 43906
Hoffer, E. D. (2017) Molecular Characterization of Ribosome-Independent Toxin Substrate Specificity. Ph.D. thesis, Emory University, Atlanta, Georgia, PhD, 196
Luo, S., and Tong, L. (2017) Molecular mechanism for the regulation of yeast separase by securin. Nature. 542, 255-259
Wohlever, M. L., Mateja, A., McGilvray, P. T., Day, K. J., and Keenan, R. J. (2017) Msp1 Is a Membrane Protein Dislocase for Tail-Anchored Proteins. Mol Cell. 67, 194-202.e6
Welsch, M. E., Kaplan, A., Chambers, J. M., Stokes, M. E., Bos, P. H., Zask, A., Zhang, Y., Sanchez-Martin, M., Badgley, M. A., Huang, C. S., Tran, T. H., Akkiraju, H., Brown, L. M., Nandakumar, R., Cremers, S., Yang, W. Seok, Tong, L., Olive, K. P., Ferrando, A., and Stockwell, B. R. (2017) Multivalent Small-Molecule Pan-RAS Inhibitors. Cell. 168, 878-889.e29
2016
Chen, Y., Seepersaud, R., Bensing, B. A., Sullam, P. M., and Rapoport, T. A. (2016) Mechanism of a cytosolic O-glycosyltransferase essential for the synthesis of a bacterial adhesion protein. Proc Natl Acad Sci U S A. 113, E1190-9
Saxton, R. A., Chantranupong, L., Knockenhauer, K. E., Schwartz, T. U., and Sabatini, D. M. (2016) Mechanism of arginine sensing by CASTOR1 upstream of mTORC1. Nature. 536, 229-33
Baranovskiy, A. G., Babayeva, N. D., Zhang, Y., Gu, J., Suwa, Y., Pavlov, Y. I., and Tahirov, T. H. (2016) Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome. J Biol Chem. 291, 10006-20
Matsuyama, B. Y., Krasteva, P. V., Baraquet, C., Harwood, C. S., Sondermann, H., and Navarro, M. V. A. S. (2016) Mechanistic insights into c-di-GMP-dependent control of the biofilm regulator FleQ from Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 113, E209-18
Clark, N. E., Katolik, A., Roberts, K. M., Taylor, A. B., Holloway, S. P., Schuermann, J. P., Montemayor, E. J., Stevens, S. W., Fitzpatrick, P. F., Damha, M. J., and P Hart, J. (2016) Metal dependence and branched RNA cocrystal structures of the RNA lariat debranching enzyme Dbr1. Proc Natl Acad Sci U S A. 113, 14727-14732

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