Found 2699 results
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Marathe, N., Nguyen, H. An, Alumasa, J. N., Nagy, A. B. Kuzmishi, Vazquez, M., Dunham, C. M., and Keiler, K. C. (2023) Antibiotic that inhibits -translation blocks binding of EF-Tu to tmRNA but not to tRNA. mBio. 10.1128/mbio.01461-23
Bulkley, D., Brandi, L., Polikanov, Y. S., Fabbretti, A., O'Connor, M., Gualerzi, C. O., and Steitz, T. A. (2014) The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation. Cell Rep. 6, 357-65
Bajic, G., and Harrison, S. C. (2020) Antibodies That Engage the Hemagglutinin Receptor-Binding Site of Influenza B Viruses. ACS Infect Dis. 10.1021/acsinfecdis.0c00726
Watanabe, A., McCarthy, K. R., Kuraoka, M., Schmidt, A. G., Adachi, Y., Onodera, T., Tonouchi, K., Caradonna, T. M., Bajic, G., Song, S., McGee, C. E., Sempowski, G. D., Feng, F., Urick, P., Kepler, T. B., Takahashi, Y., Harrison, S. C., and Kelsoe, G. (2019) Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism. Cell. 177, 1124-1135.e16
Liu, L., Iketani, S., Guo, Y., Casner, R. G., Reddem, E. R., Nair, M. S., Yu, J., Chan, J. F. - W., Wang, M., Cerutti, G., Li, Z., Morano, N. C., Castagna, C. D., Corredor, L., Chu, H., Yuan, S., Poon, V. Kwok- Man, Chan, C. Chun- Sing, Chen, Z., Luo, Y., Cunningham, M., Chavez, A., Yin, M. T., Perlin, D. S., Tsuji, M., Yuen, K. - Y., Kwong, P. D., Sheng, Z., Huang, Y., Shapiro, L., and Ho, D. D. (2022) An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses. Sci Transl Med. 10.1126/scitranslmed.abn6859
Yin, Y., Romei, M. G., Sankar, K., Pal, L. R., Hoi, K. Hon, Yang, Y., Leonard, B., Boenig, G. De Leon, Kumar, N., Matsumoto, M., Payandeh, J., Harris, S. F., Moult, J., and Lazar, G. A. (2022) Antibody interfaces revealed through structural mining. Comput Struct Biotechnol J. 20, 4952-4968
Sankhala, R. S., Dussupt, V., Chen, W. - H., Bai, H., Martinez, E. J., Jensen, J. L., Rees, P. A., Hajduczki, A., Chang, W. C., Choe, M., Yan, L., Sterling, S. L., Swafford, I., Kuklis, C., Soman, S., King, J., Corbitt, C., Zemil, M., Peterson, C. E., Mendez-Rivera, L., Townsley, S. M., Donofrio, G. C., Lal, K. G., Tran, U., Green, E. C., Smith, C., de Val, N., Laing, E. D., Broder, C. C., Currier, J. R., Gromowski, G. D., Wieczorek, L., Rolland, M., Paquin-Proulx, D., van Dyk, D., Britton, Z., Rajan, S., Loo, Y. Ming, McTamney, P. M., Esser, M. T., Polonis, V. R., Michael, N. L., Krebs, S. J., Modjarrad, K., and M Joyce, G. (2023) Antibody targeting of conserved sites of vulnerability on the SARS-CoV-2 spike receptor-binding domain. Structure. 10.1016/j.str.2023.11.015
Ferrero, S., Flores, M. D., Short, C., Vazquez, C. A., Clark, L. E., Ziegenbein, J., Zink, S., Fuentes, D., Payes, C., Batto, M. V., Collazo, M., García, C. C., Abraham, J., Cordo, S. M., Rodriguez, J. A., and Helguera, G. (2021) Antibody-Based Inhibition of Pathogenic New World Hemorrhagic Fever Mammarenaviruses by Steric Occlusion of the Human Transferrin Receptor 1 Apical Domain. J Virol. 95, e0186820
Tao, Y., Budhipramono, A., Huang, J., Fang, M., Xie, S., Kim, J., Khivansara, V., Dominski, Z., Tong, L., De Brabander, J. K., and Nijhawan, D. (2024) Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3. Cell Chem Biol. 31, 139-149.e14
Hwang, S., Shah, M., Garcia, B., Hashem, N., Davidson, A. R., Moraes, T. F., and Maxwell, K. L. (2023) Anti-CRISPR Protein AcrIIC5 Inhibits CRISPR-Cas9 by Occupying the Target DNA Binding Pocket. J Mol Biol. 435, 167991
Nicoludis, J. M., Vogt, B. E., Green, A. G., Schärfe, C. Pi, Marks, D. S., and Gaudet, R. (2016) Antiparallel protocadherin homodimers use distinct affinity- and specificity-mediating regions in cadherin repeats 1-4. Elife. 10.7554/eLife.18449
Uddin, M. Jashim, Crews, B. C., Xu, S., Ghebreselasie, K., Daniel, C. K., Kingsley, P. J., Banerjee, S., and Marnett, L. J. (2016) Antitumor Activity of Cytotoxic Cyclooxygenase-2 Inhibitors. ACS Chem Biol. 11, 3052-3060
Hallin, J., Bowcut, V., Calinisan, A., Briere, D. M., Hargis, L., Engstrom, L. D., Laguer, J., Medwid, J., Vanderpool, D., Lifset, E., Trinh, D., Hoffman, N., Wang, X., J Lawson, D., Gunn, R. J., Smith, C. R., Thomas, N. C., Martinson, M., Bergstrom, A., Sullivan, F., Bouhana, K., Winski, S., He, L., Fernandez-Banet, J., Pavlicek, A., Haling, J. R., Rahbaek, L., Marx, M. A., Olson, P., and Christensen, J. G. (2022) Anti-tumor efficacy of a potent and selective non-covalent KRAS inhibitor. Nat Med. 28, 2171-2182
Shaban, N. M., Shi, K., Lauer, K. V., Carpenter, M. A., Richards, C. M., Salamango, D., Wang, J., Lopresti, M. W., Banerjee, S., Levin-Klein, R., Brown, W. L., Aihara, H., and Harris, R. S. (2018) The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism. Mol Cell. 69, 75-86.e9
Hanke, L., Knockenhauer, K. E., R Brewer, C., van Diest, E., Schmidt, F. I., Schwartz, T. U., and Ploegh, H. L. (2016) The Antiviral Mechanism of an Influenza A Virus Nucleoprotein-Specific Single-Domain Antibody Fragment. MBio. 10.1128/mBio.01569-16
Saxton, R. A., Knockenhauer, K. E., Schwartz, T. U., and Sabatini, D. M. (2016) The apo-structure of the leucine sensor Sestrin2 is still elusive. Sci Signal. 9, ra92
Laganowsky, A., Zhao, M., Soriaga, A. B., Sawaya, M. R., Cascio, D., and Yeates, T. O. (2011) An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci. 20, 1876-90
Moss, F. J., Mahinthichaichan, P., Lodowski, D. T., Kowatz, T., Tajkhorshid, E., Engel, A., Boron, W. F., and Vahedi-Faridi, A. (2020) Aquaporin-7: A Dynamic Aquaglyceroporin With Greater Water and Glycerol Permeability Than Its Bacterial Homolog GlpF. Front Physiol. 11, 728
Simanshu, D. K., Zhai, X., Munch, D., Hofius, D., Markham, J. E., Bielawski, J., Bielawska, A., Malinina, L., Molotkovsky, J. G., Mundy, J. W., Patel, D. J., and Brown, R. E. (2014) Arabidopsis accelerated cell death 11, ACD11, is a ceramide-1-phosphate transfer protein and intermediary regulator of phytoceramide levels. Cell Rep. 6, 388-99
Xie, W., Lama, L., Yang, X., Kuryavyi, V., Bhattacharya, S., Nudelman, I., Yang, G., Ouerfelli, O., J Glickman, F., Jones, R. A., Tuschl, T., and Patel, D. J. (2023) Arabinose- and xylose-modified analogs of 2',3'-cGAMP act as STING agonists. Cell Chem Biol. 10.1016/j.chembiol.2023.07.002
Whittle, J. R. R., and Schwartz, T. U. (2009) Architectural nucleoporins Nup157/170 and Nup133 are structurally related and descend from a second ancestral element. J Biol Chem. 284, 28442-52
Ye, Q., West, A. M. V., Silletti, S., and Corbett, K. D. (2020) Architecture and self-assembly of the SARS-CoV-2 nucleocapsid protein. bioRxiv. 10.1101/2020.05.17.100685
Ye, Q., West, A. M. V., Silletti, S., and Corbett, K. D. (2020) Architecture and self-assembly of the SARS-CoV-2 nucleocapsid protein. Protein Sci. 10.1002/pro.3909
Bi, Y., Mann, E., Whitfield, C., and Zimmer, J. (2018) Architecture of a channel-forming O-antigen polysaccharide ABC transporter. Nature. 553, 361-365
Park, E., Rawson, S., Li, K., Kim, B. - W., Ficarro, S. B., Del Pino, G. Gonzalez-, Sharif, H., Marto, J. A., Jeon, H., and Eck, M. J. (2019) Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes. Nature. 575, 545-550