Publications

Found 1123 results
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2022
Liu, H., Forouhar, F., Lin, A. J., Wang, Q., Polychronidou, V., Soni, R. Kumar, Xia, X., and Stockwell, B. R. (2022) Small-molecule allosteric inhibitors of GPX4. Cell Chem Biol. 10.1016/j.chembiol.2022.11.003
Spiegelman, L., Bahn-Suh, A., Montaño, E. T., Zhang, L., Hura, G. L., Patras, K. A., Kumar, A., F Tezcan, A., Nizet, V., Tsutakawa, S. E., and Ghosh, P. (2022) Strengthening of enterococcal biofilms by Esp. PLoS Pathog. 18, e1010829
Prew, M. S., Camara, C. M., Botzanowski, T., Moroco, J. A., Bloch, N. B., Levy, H. R., Seo, H. - S., Dhe-Paganon, S., Bird, G. H., Herce, H. D., Gygi, M. A., Escudero, S., Wales, T. E., Engen, J. R., and Walensky, L. D. (2022) Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency. Nat Commun. 13, 3669
Rees, H. C., Gogacz, W., Li, N. - S., Koirala, D., and Piccirilli, J. A. (2022) Structural Basis for Fluorescence Activation by Pepper RNA. ACS Chem Biol. 17, 1866-1875
Heppner, D. E., Wittlinger, F., Beyett, T. S., Shaurova, T., Urul, D. A., Buckley, B., Pham, C. D., Schaeffner, I. K., Yang, B., Ogboo, B. C., May, E. W., Schaefer, E. M., Eck, M. J., Laufer, S. A., and Hershberger, P. A. (2022) Structural Basis for Inhibition of Mutant EGFR with Lazertinib (YH25448). ACS Med Chem Lett. 13, 1856-1863
Lyu, J., Liu, C., Zhang, T., Schrecke, S., Elam, N. P., Packianathan, C., Hochberg, G. K. A., Russell, D., Zhao, M., and Laganowsky, A. (2022) Structural basis for lipid and copper regulation of the ABC transporter MsbA. Nat Commun. 13, 7291
Krochmal, D., Shao, Y., Li, N. - S., DasGupta, S., Shelke, S. A., Koirala, D., and Piccirilli, J. A. (2022) Structural basis for substrate binding and catalysis by a self-alkylating ribozyme. Nat Chem Biol. 10.1038/s41589-021-00950-z
Syroegin, E. A., Flemmich, L., Klepacki, D., Vázquez-Laslop, N., Micura, R., and Polikanov, Y. S. (2022) Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol. Nat Struct Mol Biol. 29, 152-161
Syroegin, E. A., Aleksandrova, E. V., and Polikanov, Y. S. (2022) Structural basis for the inability of chloramphenicol to inhibit peptide bond formation in the presence of A-site glycine. Nucleic Acids Res. 50, 7669-7679
Kumar, S., Zavaliev, R., Wu, Q., Zhou, Y., Cheng, J., Dillard, L., Powers, J., Withers, J., Zhao, J., Guan, Z., Borgnia, M. J., Bartesaghi, A., Dong, X., and Zhou, P. (2022) Structural basis of NPR1 in activating plant immunity. Nature. 605, 561-566
Joseph, D., Nayak, S. Ranjan, and Penmatsa, A. (2022) Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter. EMBO J. 41, e110735
Chen, B., Basak, S., Chen, P., Zhang, C., Perry, K., Tian, S., Yu, C., Dong, M., Huang, L., Bowen, M. E., and Jin, R. (2022) Structure and conformational dynamics of toxin A. Life Sci Alliance. 10.26508/lsa.202201383
Patteson, J. B., Fortinez, C. Marie, Putz, A. T., Rodriguez-Rivas, J., L Bryant, H., Adhikari, K., Weigt, M., T Schmeing, M., and Li, B. (2022) Structure and Function of a Dehydrating Condensation Domain in Nonribosomal Peptide Biosynthesis. J Am Chem Soc. 144, 14057-14070
Patteson, J. B., Fortinez, C. Marie, Putz, A. T., Rodriguez-Rivas, J., L Bryant, H., Adhikari, K., Weigt, M., T Schmeing, M., and Li, B. (2022) Structure and Function of a Dehydrating Condensation Domain in Nonribosomal Peptide Biosynthesis. J Am Chem Soc. 144, 14057-14070
Hall, D., Giaimo, B. Daniele, Park, S. - S., Hemmer, W., Friedrich, T., Ferrante, F., Bartkuhn, M., Yuan, Z., Oswald, F., Borggrefe, T., Rual, J. - F., and Kovall, R. A. (2022) The structure, binding and function of a Notch transcription complex involving RBPJ and the epigenetic reader protein L3MBTL3.. Nucleic Acids Res. 50, 13083-13099
Chen, B., Liu, Z., Perry, K., and Jin, R. (2022) Structure of the glucosyltransferase domain of TcdA in complex with RhoA provides insights into substrate recognition. Sci Rep. 12, 9028
Cui, H., Divakaran, A., Hoell, Z. J., Ellingson, M. O., Scholtz, C. R., Zahid, H., Johnson, J. A., Griffith, E. C., Gee, C. T., Lee, A. L., Khanal, S., Shi, K., Aihara, H., Shah, V. H., Lee, R. E., Harki, D. A., and Pomerantz, W. C. K. (2022) A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes. J Med Chem. 10.1021/acs.jmedchem.1c01779
Grigg, J. C., Price, I. R., and Ke, A. (2022) tRNA Fusion to Streamline RNA Structure Determination: Case Studies in Probing Aminoacyl-tRNA Sensing Mechanisms by the T-Box Riboswitch. doi:10.3390/cryst12050694
Lee, B. U., Papoutsis, B. M., Wong, N. Y., Piacentini, J., Kearney, C., Huggins, N. A., Cruz, N., Ng, T. T., Hao, K. Heather, Kramer, J. S., Fenlon, E. E., Nerenberg, P. S., Phillips-Piro, C. M., and Brewer, S. H. (2022) Unraveling Complex Local Protein Environments with 4-Cyano-l-phenylalanine. J Phys Chem B. 126, 8957-8969
Lee, B. U., Papoutsis, B. M., Wong, N. Y., Piacentini, J., Kearney, C., Huggins, N. A., Cruz, N., Ng, T. T., Hao, K. Heather, Kramer, J. S., Fenlon, E. E., Nerenberg, P. S., Phillips-Piro, C. M., and Brewer, S. H. (2022) Unraveling Complex Local Protein Environments with 4-Cyano-l-phenylalanine. J Phys Chem B. 126, 8957-8969
Lee, B. U., Papoutsis, B. M., Wong, N. Y., Piacentini, J., Kearney, C., Huggins, N. A., Cruz, N., Ng, T. T., Hao, K. Heather, Kramer, J. S., Fenlon, E. E., Nerenberg, P. S., Phillips-Piro, C. M., and Brewer, S. H. (2022) Unraveling Complex Local Protein Environments with 4-Cyano-l-phenylalanine. J Phys Chem B. 126, 8957-8969
Smiley, A. T., Tompkins, K. J., Pawlak, M. R., Krueger, A. J., Evans, R. L., Shi, K., Aihara, H., and Gordon, W. R. (2022) Watson-Crick Base-Pairing Requirements for ssDNA Recognition and Processing in Replication-Initiating HUH Endonucleases. mBio. 10.1128/mbio.02587-22

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