Publications

Found 194 results
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Lee, K., Zhong, X., Gu, S., Kruel, A. Magdalena, Dorner, M. B., Perry, K., Rummel, A., Dong, M., and Jin, R. (2014) Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex. Science. 344, 1405-10
Lee, S. - J., Sung, R. - J., and Verdine, G. L. (2019) Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System. Research (Wash D C). 2019, 5641746
Lavoie, H., Sahmi, M., Maisonneuve, P., Marullo, S. A., Thevakumaran, N., Jin, T., Kurinov, I., Sicheri, F., and Therrien, M. (2018) MEK drives BRAF activation through allosteric control of KSR proteins. Nature. 10.1038/nature25478
Latorraca, N. R., Fastman, N. M., Venkatakrishnan, A. J., Frommer, W. B., Dror, R. O., and Feng, L. (2017) Mechanism of Substrate Translocation in an Alternating Access Transporter. Cell. 169, 96-107.e12
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Košutić, M., Neuner, S., Ren, A., Flür, S., Wunderlich, C., Mairhofer, E., Vušurović, N., Seikowski, J., Breuker, K., Höbartner, C., Patel, D. J., Kreutz, C., and Micura, R. (2015) A Mini-Twister Variant and Impact of Residues/Cations on the Phosphodiester Cleavage of this Ribozyme Class. Angew Chem Int Ed Engl. 54, 15128-15133
Kim, M., Sandford, E., Gatica, D., Qiu, Y., Liu, X., Zheng, Y., Schulman, B. A., Xu, J., Semple, I., Ro, S. - H., Kim, B., R Mavioglu, N., Tolun, A., Jipa, A., Takats, S., Karpati, M., Li, J. Z., Yapici, Z., Juhasz, G., Lee, J. Hee, Klionsky, D. J., and Burmeister, M. (2016) Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay. Elife. 10.7554/eLife.12245
Kamadurai, H. B., Qiu, Y., Deng, A., Harrison, J. S., Macdonald, C., Actis, M., Rodrigues, P., Miller, D. J., Souphron, J., Lewis, S. M., Kurinov, I., Fujii, N., Hammel, M., Piper, R., Kuhlman, B., and Schulman, B. A. (2013) Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3. Elife. 2, e00828
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Ji, Q., Zhang, L., Jones, M. B., Sun, F., Deng, X., Liang, H., Cho, H., Brugarolas, P., Gao, Y. N., Peterson, S. N., Lan, L., Bae, T., and He, C. (2013) Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR. Proc Natl Acad Sci U S A. 110, 5010-5
Ji, X., Wu, Y., Yan, J., Mehrens, J., Yang, H., DeLucia, M., Hao, C., Gronenborn, A. M., Skowronski, J., Ahn, J., and Xiong, Y. (2013) Mechanism of allosteric activation of SAMHD1 by dGTP. Nat Struct Mol Biol. 20, 1304-9
Jensen, J. L., Balbo, A., Neau, D. B., Chakravarthy, S., Zhao, H., Sinha, S. C., and Colbert, C. L. (2015) Mechanistic Implications of the Unique Structural Features and Dimerization of the Cytoplasmic Domain of the Pseudomonas Sigma Regulator, PupR. Biochemistry. 54, 5867-77
Jenkins, A. L., Zhang, Y., Ealick, S. E., and Begley, T. P. (2008) Mutagenesis studies on TenA: a thiamin salvage enzyme from Bacillus subtilis. Bioorg Chem. 36, 29-32
Jana, S., Shang, J., Hong, J. Young, Fenwick, M. K., Puri, R., Lu, X., Melnick, A. M., Li, M., and Lin, H. (2024) A Mitochondria-Targeting SIRT3 Inhibitor with Activity against Diffuse Large B Cell Lymphoma. J Med Chem. 67, 15428-15437
Jain, R., Choudhury, J. Roy, Buku, A., Johnson, R. E., Prakash, L., Prakash, S., and Aggarwal, A. K. (2017) Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-ι.. Sci Rep. 7, 43904
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Ivanova, M. I., Sievers, S. A., Sawaya, M. R., Wall, J. S., and Eisenberg, D. (2009) Molecular basis for insulin fibril assembly. Proc Natl Acad Sci U S A. 106, 18990-5
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Huang, H. - T., Seo, H. - S., Zhang, T., Wang, Y., Jiang, B., Li, Q., Buckley, D. L., Nabet, B., Roberts, J. M., Paulk, J., Dastjerdi, S., Winter, G. E., McLauchlan, H., Moran, J., Bradner, J. E., Eck, M. J., Dhe-Paganon, S., Zhao, J. J., and Gray, N. S. (2017) MELK is not necessary for the proliferation of basal-like breast cancer cells. Elife. 10.7554/eLife.26693
Huang, F., Lu, X., Yu, C., Sliz, P., Wang, L., and Zhu, B. (2021) Molecular Dissection of the Primase and Polymerase Activities of Deep-Sea Phage NrS-1 Primase-Polymerase. Front Microbiol. 12, 766612
Horenkamp, F. A., Valverde, D. P., Nunnari, J., and Reinisch, K. M. (2018) Molecular basis for sterol transport by StART-like lipid transfer domains. EMBO J. 10.15252/embj.201798002
Hong, Z., Adlakha, J., Wan, N., Guinn, E., Giska, F., Gupta, K., Melia, T. J., and Reinisch, K. M. (2022) Mitoguardin-2-mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation. J Cell Biol. 10.1083/jcb.202207022
Hong, S., Sunita, S., Maehigashi, T., Hoffer, E. D., Dunkle, J. A., and Dunham, C. M. (2018) Mechanism of tRNA-mediated +1 ribosomal frameshifting. Proc Natl Acad Sci U S A. 10.1073/pnas.1809319115
Hoffer, E. D. (2017) Molecular Characterization of Ribosome-Independent Toxin Substrate Specificity. Ph.D. thesis, Emory University, Atlanta, Georgia, PhD, 196
Hattori, M., and Gouaux, E. (2012) Molecular mechanism of ATP binding and ion channel activation in P2X receptors. Nature. 485, 207-12
Hamilton, K., and Tong, L. (2020) Molecular mechanism for the interaction between human CPSF30 and hFip1. Genes Dev. 10.1101/gad.343814.120
Ha, B. Hak, Yigit, S., Natarajan, N., Morse, E. M., Calderwood, D. A., and Boggon, T. J. (2022) Molecular basis for integrin adhesion receptor binding to p21-activated kinase 4 (PAK4). Commun Biol. 5, 1257
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Guzman, M., Rugel, A., Tarpley, R. S., Cao, X., McHardy, S. F., LoVerde, P. T., and Taylor, A. B. (2020) Molecular basis for hycanthone drug action in schistosome parasites. Mol Biochem Parasitol. 236, 111257
Gu, W., Gao, S., Wang, H., Fleming, K. D., Hoffmann, R. M., Yang, J. Won, Patel, N. M., Choi, Y. Mi, Burke, J. E., Reue, K., and Airola, M. V. (2021) The middle lipin domain adopts a membrane-binding dimeric protein fold. Nat Commun. 12, 4718

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