Publications
(2012) Mechanistic and structural analyses of the role of His67 in the yeast polyamine oxidase Fms1. Biochemistry. 51, 4888-97
(2012) Mechanistic and structural analyses of the roles of active site residues in yeast polyamine oxidase Fms1: characterization of the N195A and D94N enzymes. Biochemistry. 51, 8690-7
(2012) Mechanistic insights into validoxylamine A 7'-phosphate synthesis by VldE using the structure of the entire product complex. PLoS One. 7, e44934
(2012) Metal-organic frameworks incorporating copper-complexed rotaxanes. Angew Chem Int Ed Engl. 51, 2160-3
(2012) Molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex. Proc Natl Acad Sci U S A. 109, 15241-6
(2012) Molecular basis of the fructose-2,6-bisphosphatase reaction of PFKFB3: transition state and the C-terminal function. Proteins. 80, 1143-53
(2012) Molecular mechanism of ATP binding and ion channel activation in P2X receptors. Nature. 485, 207-12
(2011) Mechanism of activation gating in the full-length KcsA K+ channel. Proc Natl Acad Sci U S A. 108, 11896-9
(2011) Molecular architecture of the transport channel of the nuclear pore complex. Cell. 147, 590-602
(2011) MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a. Nat Commun. 2, 533
(2011) Multimeric assembly and biochemical characterization of the Trax-translin endonuclease complex. Nat Struct Mol Biol. 18, 658-64
(2010) The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer. Nat Chem Biol. 6, 595-601
(2010) Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes. Protein Sci. 19, 507-19
(2010) Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4. Nat Struct Mol Biol. 17, 379-88
(2010) Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function. RNA. 16, 2319-24
(2010) Molecular level insights into thermally induced α-chymotrypsinogen A amyloid aggregation mechanism and semiflexible protofibril morphology.. Biochemistry. 49, 10553-64
(2010) The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments. Cell. 142, 556-67
(2009) Molecular architecture of the Nup84-Nup145C-Sec13 edge element in the nuclear pore complex lattice. Nat Struct Mol Biol. 16, 1173-7
(2009) The molecular basis for the regulation of the cap-binding complex by the importins. Nat Struct Mol Biol. 16, 930-7
(2009) Molecular basis of substrate selection by the N-end rule adaptor protein ClpS. Proc Natl Acad Sci U S A. 106, 8888-93