Publications

Found 10 results
Filters: Author is Lv, Zongyang  [Clear All Filters]
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A
Rut, W., Lv, Z., Zmudzinski, M., Patchett, S., Nayak, D., Snipas, S. J., Oualid, F. El, Huang, T. T., Békés, M., Drag, M., and Olsen, S. K. (2020) Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design. Sci Adv. 10.1126/sciadv.abd4596
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Lv, Z., Williams, K. M., Yuan, L., Atkison, J. H., and Olsen, S. K. (2018) Crystal structure of a human ubiquitin E1-ubiquitin complex reveals conserved functional elements essential for activity. J Biol Chem. 10.1074/jbc.RA118.003975
Yuan, L., Lv, Z., Adams, M. J., and Olsen, S. K. (2021) Crystal structures of an E1-E2-ubiquitin thioester mimetic reveal molecular mechanisms of transthioesterification. Nat Commun. 12, 2370
Yuan, L., Gao, F., Lv, Z., Nayak, D., Nayak, A., Bury, P. Dos Santos, Cano, K. E., Jia, L., Oleinik, N., Atilgan, F. Cansu, Ogretmen, B., Williams, K. M., Davies, C., Oualid, F. El, Wasmuth, E. V., and Olsen, S. K. (2022) Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6. Nat Commun. 13, 4880
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Nayak, D., Lv, D., Yuan, Y., Zhang, P., Hu, W., Nayak, A., Ruben, E. A., Lv, Z., Sung, P., Hromas, R., Zheng, G., Zhou, D., and Olsen, S. K. (2024) Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL. Nat Commun. 15, 2743
Lv, Z., Yuan, L., Atkison, J. H., Aldana-Masangkay, G., Chen, Y., and Olsen, S. K. (2017) Domain alternation and active site remodeling are conserved structural features of ubiquitin E1. J Biol Chem. 292, 12089-12099
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Lv, Z., Yuan, L., Atkison, J. H., Williams, K. M., Vega, R., E Sessions, H., Divlianska, D. B., Davies, C., Chen, Y., and Olsen, S. K. (2018) Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme. Nat Commun. 9, 5145
Patchett, S., Lv, Z., Rut, W., Békés, M., Drag, M., Olsen, S. K., and Huang, T. T. (2021) A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease. Cell Rep. 36, 109754
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Lv, Z., Rickman, K. A., Yuan, L., Williams, K., Selvam, S. Panneer, Woosley, A. N., Howe, P. H., Ogretmen, B., Smogorzewska, A., and Olsen, S. K. (2017) S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity.. Mol Cell. 65, 699-714.e6
Yuan, L., Lv, Z., Atkison, J. H., and Olsen, S. K. (2017) Structural insights into the mechanism and E2 specificity of the RBR E3 ubiquitin ligase HHARI. Nat Commun. 8, 211