Publications
Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains. ACS Chem Biol. 10.1021/acschembio.7b00638
(2018) Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1. Elife. 10.7554/eLife.20070
(2017) Structural and biochemical analysis of DNA helix invasion by the bacterial 8-oxoguanine DNA glycosylase MutM. J Biol Chem. 288, 10012-23
(2013) Structural and biochemical analysis of human ADP-ribosyl-acceptor hydrolase 3 (ARH3) reveals the basis of metal selectivity and different roles for the two Mg ions. J Biol Chem. 10.1016/j.jbc.2021.100692
(2021) Structural and Biochemical Characterization of 6-Hydroxynicotinic Acid 3-Monooxygenase, A Novel Decarboxylative Hydroxylase Involved in Aerobic Nicotinate Degradation. Biochemistry. 55, 3432-46
(2016) Structural and Biochemical Characterization of Aldehyde Dehydrogenase 12, the Last Enzyme of Proline Catabolism in Plants. J Mol Biol. 431, 576-592
(2019) Structural and Biochemical Characterization of the Flavin-Dependent Siderophore-Interacting Protein from . ACS Omega. 6, 18537-18547
(2021) Structural and biochemical characterization of the protease domain of the mosaic botulinum neurotoxin type HA. Pathog Dis. 10.1093/femspd/fty044
(2018) Structural and biochemical characterization of the salicylyl-acyltranferase SsfX3 from a tetracycline biosynthetic pathway. J Biol Chem. 286, 41539-51
(2011) Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel. Biochemistry. 51, 6195-206
(2012) Structural and biochemical insights into lipid transport by VPS13 proteins. J Cell Biol. 10.1083/jcb.202202030
(2022) Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase from . Biochemistry. 58, 5011-5021
(2019) Structural and biochemical studies of the open state of Lys48-linked diubiquitin. Biochim Biophys Acta. 1823, 2046-56
(2012) Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization. J Biol Chem. 286, 24417-25
(2011) Structural and computational studies of the Staphylococcus aureus sortase B-substrate complex reveal a substrate-stabilized oxyanion hole. J Biol Chem. 289, 8891-902
(2014) Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep. 13, 1800-13
(2015) Structural and dynamic basis of substrate permissiveness in hydroxycinnamoyltransferase (HCT). PLoS Comput Biol. 14, e1006511
(2018) Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy. J Biol Chem. 292, 11154-11164
(2017) Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1. Nat Struct Mol Biol. 16, 876-82
(2009) Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus. Proc Natl Acad Sci U S A. 116, 20707-20715
(2019) Structural and functional analyses reveal the contributions of the C- and N-lobes of Argonaute protein to selectivity of RNA target cleavage. J Biol Chem. 10.1074/jbc.RA117.001051
(2018) Structural and Functional Analysis of BipA, a Regulator of Virulence in Enteropathogenic Escherichia coli. J Biol Chem. 290, 20856-64
(2015) Structural and Functional Analysis of E. coli Cyclopropane Fatty Acid Synthase.. Structure. 10.1016/j.str.2018.06.008
(2018) Structural and functional analysis of FIP2 binding to the endosome-localised Rab25 GTPase. Biochim Biophys Acta. 1834, 2679-90
(2013) Structural and functional analysis of the transcriptional regulator Rv3066 of Mycobacterium tuberculosis. Nucleic Acids Res. 40, 9340-55
(2012)