Publications

Found 2819 results
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Mehta, R. S., Mayers, J. R., Zhang, Y., Bhosle, A., Glasser, N. R., Nguyen, L. H., Ma, W., Bae, S., Branck, T., Song, K., Sebastian, L., Pacheco, J. Avila, Seo, H. - S., Clish, C., Dhe-Paganon, S., Ananthakrishnan, A. N., Franzosa, E. A., Balskus, E. P., Chan, A. T., and Huttenhower, C. (2023) Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease. Nat Med. 29, 700-709
Chehayeb, R. Jaber, Wang, J., Stiegler, A. L., and Boggon, T. J. (2020) The GTPase-activating protein p120RasGAP has an evolutionarily conserved "FLVR-unique" SH2 domain. J Biol Chem. 295, 10511-10521
Zhao, C., and Pyle, A. Marie (2017) The group II intron maturase: a reverse transcriptase and splicing factor go hand in hand. Curr Opin Struct Biol. 47, 30-39
Huang, H., Suslov, N. B., Li, N. - S., Shelke, S. A., Evans, M. E., Koldobskaya, Y., Rice, P. A., and Piccirilli, J. A. (2014) A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat Chem Biol. 10, 686-91
Hong, J. Young, Price, I. Robert, Bai, J. Jingyi, and Lin, H. (2019) A Glycoconjugated SIRT2 Inhibitor with Aqueous Solubility Allows Structure-Based Design of SIRT2 Inhibitors. ACS Chem Biol. 14, 1802-1810
Paul, D., O'Leary, S. E., Rajashankar, K., Bu, W., Toms, A., Settembre, E. C., Sanders, J. M., Begley, T. P., and Ealick, S. E. (2010) Glycal formation in crystals of uridine phosphorylase. Biochemistry. 49, 3499-509
Chae, P. Seok, Rana, R. R., Gotfryd, K., Rasmussen, S. G. F., Kruse, A. C., Cho, K. Ho, Capaldi, S., Carlsson, E., Kobilka, B., Loland, C. J., Gether, U., Banerjee, S., Byrne, B., Lee, J. K., and Gellman, S. H. (2013) Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study. Chem Commun (Camb). 49, 2287-9
Mieher, J. L., Larson, M. R., Schormann, N., Purushotham, S., Wu, R., Rajashankar, K. R., Wu, H., and Deivanayagam, C. (2018) Glucan Binding Protein C of Mediates both Sucrose-Independent and Sucrose-Dependent Adherence. Infect Immun. 10.1128/IAI.00146-18
Ren, A., Rajashankar, K. R., and Patel, D. J. (2015) Global RNA Fold and Molecular Recognition for a pfl Riboswitch Bound to ZMP, a Master Regulator of One-Carbon Metabolism. Structure. 23, 1375-1381
Yoo, J., Mashalidis, E. H., C Y Kuk, A., Yamamoto, K., Kaeser, B., Ichikawa, S., and Lee, S. - Y. (2018) GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation. Nat Struct Mol Biol. 10.1038/s41594-018-0031-y
Laniado, J., Cannon, K. A., Miller, J. E., Sawaya, M. R., McNamara, D. E., and Yeates, T. O. (2021) Geometric Lessons and Design Strategies for Nanoscale Protein Cages. ACS Nano. 10.1021/acsnano.0c07167
Schwer, B., Garg, A., Jacewicz, A., and Shuman, S. (2021) Genetic screen for suppression of transcriptional interference identifies a gain-of-function mutation in Pol2 termination factor Seb1. Proc Natl Acad Sci U S A. 10.1073/pnas.2108105118
Schwer, B., Ghosh, A., Sanchez, A. M., Lima, C. D., and Shuman, S. (2015) Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1. RNA. 21, 1135-46
Carrell, C. J., Ma, J. K., Antholine, W. E., Hosler, J. P., F Mathews, S., and Davidson, V. L. (2007) Generation of novel copper sites by mutation of the axial ligand of amicyanin. Atomic resolution structures and spectroscopic properties. Biochemistry. 46, 1900-12
Benveniste, P. M., Roy, S., Nakatsugawa, M., L Y Chen, E., Nguyen, L., Millar, D. G., Ohashi, P. S., Hirano, N., Adams, E. J., and Zúñiga-Pflücker, J. Carlos (2018) Generation and molecular recognition of melanoma-associated antigen-specific human γδ T cells.. Sci Immunol. 10.1126/sciimmunol.aav4036
Goldgur, Y., Susi, P., Karelehto, E., Sanmark, H., Lamminmäki, U., Oricchio, E., Wendel, H. - G., Nikolov, D. B., and Himanen, J. P. (2014) Generation and characterization of a single-chain anti-EphA2 antibody. Growth Factors. 32, 214-22
Gantt, S. M. Lucy, Decroos, C., Lee, M. S., Gullett, L. E., Bowman, C. M., Christianson, D. W., and Fierke, C. A. (2016) General Base-General Acid Catalysis in Human Histone Deacetylase 8. Biochemistry. 55, 820-32
Mukherjee, T., McCulloch, K. M., Ealick, S. E., and Begley, T. P. (2007) Gene identification and structural characterization of the pyridoxal 5'-phosphate degradative protein 3-hydroxy-2-methylpyridine-4,5-dicarboxylate decarboxylase from mesorhizobium loti MAFF303099. Biochemistry. 46, 13606-15
Cao, Y., Pan, Y., Huang, H., Jin, X., Levin, E. J., Kloss, B., and Zhou, M. (2013) Gating of the TrkH ion channel by its associated RCK protein TrkA. Nature. 496, 317-22
Yoder, N., Yoshioka, C., and Gouaux, E. (2018) Gating mechanisms of acid-sensing ion channels. Nature. 10.1038/nature25782
Moghadasi, S. Arad, Esler, M. A., Otsuka, Y., Becker, J. T., Moraes, S. N., Anderson, C. B., Chamakuri, S., Belica, C., Wick, C., Harki, D. A., Young, D. W., Scampavia, L., Spicer, T. P., Shi, K., Aihara, H., Brown, W. L., and Harris, R. S. (2022) Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 M/3CL in Living Cells. mBio. 10.1128/mbio.00784-22
McCarthy, K. R., Schmidt, A. G., Kirmaier, A., Wyand, A. L., Newman, R. M., and Johnson, W. E. (2013) Gain-of-sensitivity mutations in a Trim5-resistant primary isolate of pathogenic SIV identify two independent conserved determinants of Trim5α specificity.. PLoS Pathog. 9, e1003352

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