Publications
Sequence-dependent structural changes in a self-assembling DNA oligonucleotide. Acta Crystallogr D Biol Crystallogr. 71, 2471-8
(2015) Determining the Crystal Structure of TRPV6. in Calcium Entry Channels in Non-Excitable Cells, pp. 275-292, Calcium Entry Channels in Non-Excitable Cells, Boca Raton (FL), 10.1201/9781315152592-14
(2018) (2016) Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation. ACS Med Chem Lett. 11, 2268-2276
(2020) H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex.. Nature. 534, 714-718
(2016) Crystallization and preliminary X-ray diffraction analysis of three recombinant mutants of Vaccinia virus uracil DNA glycosylase. Acta Crystallogr Sect F Struct Biol Cryst Commun. 69, 295-301
(2013) Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis. Nature. 510, 427-31
(2014) Protein crystal structure obtained at 2.9 Å resolution from injecting bacterial cells into an X-ray free-electron laser beam.. Proc Natl Acad Sci U S A. 111, 12769-74
(2014) (2016) (2016) (2016) X-ray structure of a hydroxylase-regulatory protein complex from a hydrocarbon-oxidizing multicomponent monooxygenase, Pseudomonas sp. OX1 phenol hydroxylase. Biochemistry. 45, 15392-404
(2006) Substrate Preferences Establish the Order of Cell Wall Assembly in Staphylococcus aureus. J Am Chem Soc. 140, 2442-2445
(2018) Structure and reconstitution of a hydrolase complex that may release peptidoglycan from the membrane after polymerization. Nat Microbiol. 10.1038/s41564-020-00808-5
(2020) Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer. Nature. 510, 552-5
(2014) The full-length structure of Thermus scotoductus OLD defines the ATP hydrolysis properties and catalytic mechanism of Class 1 OLD family nucleases. Nucleic Acids Res. 48, 2762-2776
(2020) Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage. Nucleic Acids Res. 47, 9448-9463
(2019) Polerovirus N-terminal readthrough domain structures reveal molecular strategies for mitigating virus transmission by aphids. Nat Commun. 13, 6368
(2022) (2014) (2012) Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets. Elife. 10.7554/eLife.07646
(2015) Structure of a herpesvirus-encoded cysteine protease reveals a unique class of deubiquitinating enzymes. Mol Cell. 25, 677-87
(2007) A chimeric prokaryotic pentameric ligand-gated channel reveals distinct pathways of activation. J Gen Physiol. 146, 323-40
(2015) Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit. RNA. 9, 1345-52
(2003) Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody. Proc Natl Acad Sci U S A. 110, 264-9
(2013)