Publications
Found 13 results
Filters: Author is Schmeing, T Martin [Clear All Filters]
Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid. Nature. 565, 112-117
(2019) Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit. RNA. 9, 1345-52
(2003) Structures of a dimodular nonribosomal peptide synthetase reveal conformational flexibility. Science. 10.1126/science.aaw4388
(2019) Structures and function of the amino acid polymerase cyanophycin synthetase. Nat Chem Biol. 17, 1101-1110
(2021) Structures and function of a tailoring oxidase in complex with a nonribosomal peptide synthetase module. Nat Commun. 13, 548
(2022) The structure of cyanophycinase in complex with a cyanophycin degradation intermediate. Biochim Biophys Acta Gen Subj. 1866, 130217
(2022) Structure and Function of a Dehydrating Condensation Domain in Nonribosomal Peptide Biosynthesis. J Am Chem Soc. 144, 14057-14070
(2022) Structural Insight into a Novel Formyltransferase and Evolution to a Nonribosomal Peptide Synthetase Tailoring Domain. ACS Chem Biol. 10.1021/acschembio.8b00739
(2018) Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis. Nat Chem Biol. 10.1038/s41589-020-0481-5
(2020) (2024)
Efficacy of epetraborole against Mycobacterium abscessus is increased with norvaline. PLoS Pathog. 17, e1009965
(2021) Discovery of cyanophycin dipeptide hydrolase enzymes suggests widespread utility of the natural biopolymer cyanophycin. Proc Natl Acad Sci U S A. 120, e2216547120
(2023) Design, synthesis and in vitro evaluation of novel SARS-CoV-2 3CL covalent inhibitors.. Eur J Med Chem. 229, 114046
(2022)