Publications
Chemical logic of MraY inhibition by antibacterial nucleoside natural products. Nat Commun. 10, 2917
(2019) Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis. Science. 341, 1012-1016
(2013) Design and Evaluation of Pyridinyl Sulfonyl Piperazine LpxH Inhibitors with Potent Antibiotic Activity Against Enterobacterales. JACS Au. 4, 4383-4393
(2024) Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief. Nat Commun. 15, 10738
(2024) Development of LpxH inhibitors chelating the active site di-manganese metal cluster of LpxH. ChemMedChem. 10.1002/cmdc.202300023
(2023) Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. Elife. 3, e03604
(2014) Structural basis of the UDP-diacylglucosamine pyrophosphohydrolase LpxH inhibition by sulfonyl piperazine antibiotics. Proc Natl Acad Sci U S A. 117, 4109-4116
(2020) (2016) (2020)