Publications

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Journal Article
Joseph, D., Nayak, S. Ranjan, and Penmatsa, A. (2022) Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter. EMBO J. 41, e110735
Serganov, A., Huang, L., and Patel, D. J. (2008) Structural insights into amino acid binding and gene control by a lysine riboswitch. Nature. 455, 1263-7
Yang, H., Wang, J., Jia, X., McNatt, M. W., Zang, T., Pan, B., Meng, W., Wang, H. - W., Bieniasz, P. D., and Xiong, Y. (2010) Structural insight into the mechanisms of enveloped virus tethering by tetherin. Proc Natl Acad Sci U S A. 107, 18428-32
Tripathi, S., and Paukstelis, P. J. (2016) Structural Implications of Homopyrimidine Base Pairs in the Parallel-Stranded d(YGA) Motif. Chembiochem. 17, 1177-83
Sander, C. L., Luu, J., Kim, K., Furkert, D., Jang, K., Reichenwallner, J., Kang, M. S., Lee, H. - J., Eger, B. T., Choe, H. - W., Fiedler, D., Ernst, O. P., Kim, Y. Ju, Palczewski, K., and Kiser, P. D. (2021) Structural evidence for visual arrestin priming via complexation of phosphoinositols. Structure. 10.1016/j.str.2021.10.002
Edani, B. H., Grabińska, K. A., Zhang, R., Park, E. Joo, Siciliano, B., Surmacz, L., Ha, Y., and Sessa, W. C. (2020) Structural elucidation of the -prenyltransferase NgBR/DHDDS complex reveals insights in regulation of protein glycosylation. Proc Natl Acad Sci U S A. 10.1073/pnas.2008381117
Rudolph, M. J., Davis, S. A., Haque, H. M. Emranul, Weis, D. D., Vance, D. J., Piazza, C. Lyn, Ejemel, M., Cavacini, L., Wang, Y., M Mbow, L., Gilmore, R. D., and Mantis, N. J. (2023) Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi. mBio. 10.1128/mbio.02981-22
Pandya, R. K., Partridge, J. R., Love, K. Routenberg, Schwartz, T. U., and Ploegh, H. L. (2010) A structural element within the HUWE1 HECT domain modulates self-ubiquitination and substrate ubiquitination activities. J Biol Chem. 285, 5664-73
Pandya, R. K., Partridge, J. R., Love, K. Routenberg, Schwartz, T. U., and Ploegh, H. L. (2010) A structural element within the HUWE1 HECT domain modulates self-ubiquitination and substrate ubiquitination activities. J Biol Chem. 285, 5664-73
Pandya, R. K., Partridge, J. R., Love, K. Routenberg, Schwartz, T. U., and Ploegh, H. L. (2010) A structural element within the HUWE1 HECT domain modulates self-ubiquitination and substrate ubiquitination activities. J Biol Chem. 285, 5664-73
Kenoth, R., Simanshu, D. K., Kamlekar, R. Kanth, Pike, H. M., Molotkovsky, J. G., Benson, L. M., H Bergen, R., Prendergast, F. G., Malinina, L., Venyaminov, S. Y., Patel, D. J., and Brown, R. E. (2010) Structural determination and tryptophan fluorescence of heterokaryon incompatibility C2 protein (HET-C2), a fungal glycolipid transfer protein (GLTP), provide novel insights into glycolipid specificity and membrane interaction by the GLTP fold. J Biol Chem. 285, 13066-78
Kenoth, R., Simanshu, D. K., Kamlekar, R. Kanth, Pike, H. M., Molotkovsky, J. G., Benson, L. M., H Bergen, R., Prendergast, F. G., Malinina, L., Venyaminov, S. Y., Patel, D. J., and Brown, R. E. (2010) Structural determination and tryptophan fluorescence of heterokaryon incompatibility C2 protein (HET-C2), a fungal glycolipid transfer protein (GLTP), provide novel insights into glycolipid specificity and membrane interaction by the GLTP fold. J Biol Chem. 285, 13066-78
Kenoth, R., Simanshu, D. K., Kamlekar, R. Kanth, Pike, H. M., Molotkovsky, J. G., Benson, L. M., H Bergen, R., Prendergast, F. G., Malinina, L., Venyaminov, S. Y., Patel, D. J., and Brown, R. E. (2010) Structural determination and tryptophan fluorescence of heterokaryon incompatibility C2 protein (HET-C2), a fungal glycolipid transfer protein (GLTP), provide novel insights into glycolipid specificity and membrane interaction by the GLTP fold. J Biol Chem. 285, 13066-78
Pruitt, R. N., Chumbler, N. M., Rutherford, S. A., Farrow, M. A., Friedman, D. B., Spiller, B., and D Lacy, B. (2012) Structural determinants of Clostridium difficile toxin A glucosyltransferase activity. J Biol Chem. 287, 8013-20
Bradley, T., Fera, D., Bhiman, J., Eslamizar, L., Lu, X., Anasti, K., Zhang, R., Sutherland, L. L., Scearce, R. M., Bowman, C. M., Stolarchuk, C., Lloyd, K. E., Parks, R., Eaton, A., Foulger, A., Nie, X., Karim, S. S. Abdool, Barnett, S., Kelsoe, G., Kepler, T. B., S Alam, M., Montefiori, D. C., M Moody, A., Liao, H. - X., Morris, L., Santra, S., Harrison, S. C., and Haynes, B. F. (2016) Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Rep. 14, 43-54
Toms, A. V., Haas, A. L., Park, J. - H., Begley, T. P., and Ealick, S. E. (2005) Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II. Biochemistry. 44, 2319-29
Schiltz, C. J., Lee, A., Partlow, E. A., Hosford, C. J., and Chappie, J. S. (2019) Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage. Nucleic Acids Res. 47, 9448-9463
Zheng, C., Page, R. C., Das, V., Nix, J. C., Wigren, E., Misra, S., and Zhang, B. (2013) Structural characterization of carbohydrate binding by LMAN1 protein provides new insight into the endoplasmic reticulum export of factors V (FV) and VIII (FVIII). J Biol Chem. 288, 20499-509
Yasuda, H., Park, E., Yun, C. -hong, Sng, N. J., Lucena-Araujo, A. R., Yeo, W. - L., Huberman, M. S., Cohen, D. W., Nakayama, S., Ishioka, K., Yamaguchi, N., Hanna, M., Oxnard, G. R., Lathan, C. S., Moran, T., Sequist, L. V., Chaft, J. E., Riely, G. J., Arcila, M. E., Soo, R. A., Meyerson, M., Eck, M. J., Kobayashi, S. S., and Costa, D. B. (2013) Structural, biochemical, and clinical characterization of epidermal growth factor receptor (EGFR) exon 20 insertion mutations in lung cancer. Sci Transl Med. 5, 216ra177
Huang, H., Deng, Z., Vladimirova, O., Wiedmer, A., Lu, F., Lieberman, P. M., and Patel, D. J. (2016) Structural basis underlying viral hijacking of a histone chaperone complex. Nat Commun. 7, 12707
Teplova, M., Farazi, T. A., Tuschl, T., and Patel, D. J. (2016) Structural basis underlying CAC RNA recognition by the RRM domain of dimeric RNA-binding protein RBPMS. Q Rev Biophys. 49, e1
Scrima, A., Konícková, R., Czyzewski, B. K., Kawasaki, Y., Jeffrey, P. D., Groisman, R., Nakatani, Y., Iwai, S., Pavletich, N. P., and Thomä, N. H. (2008) Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell. 135, 1213-23
Owens, T. W., Taylor, R. J., Pahil, K. S., Bertani, B. R., Ruiz, N., Kruse, A. C., and Kahne, D. (2019) Structural basis of unidirectional export of lipopolysaccharide to the cell surface. Nature. 567, 550-553
Phillips, C. M., Schreiter, E. R., Guo, Y., Wang, S. C., Zamble, D. B., and Drennan, C. L. (2008) Structural basis of the metal specificity for nickel regulatory protein NikR. Biochemistry. 47, 1938-46
Dhindwal, S., Gomez-Gil, L., Neau, D. B., Pham, T. Thanh My, Sylvestre, M., Eltis, L. D., Bolin, J. T., and Kumar, P. (2016) Structural Basis of the Enhanced Pollutant-Degrading Capabilities of an Engineered Biphenyl Dioxygenase. J Bacteriol. 198, 1499-512

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