Publications
Found 33 results
Filters: Author is Begley, Tadhg P [Clear All Filters]
Active-site models for complexes of quinolinate synthase with substrates and intermediates. Acta Crystallogr D Biol Crystallogr. 69, 1685-96
(2013) (2017) (2016)
(2010) (2008)
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(2007) (2010)
HMP binding protein ThiY and HMP-P synthase THI5 are structural homologues. Biochemistry. 49, 8929-36
(2010) Mutagenesis studies on TenA: a thiamin salvage enzyme from Bacillus subtilis. Bioorg Chem. 36, 29-32
(2008) (2015)
(2012)
Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily. Nat Chem Biol. 4, 758-65
(2008) (2013) Structural and mechanistic studies of HpxO, a novel flavin adenine dinucleotide-dependent urate oxidase from Klebsiella pneumoniae. Biochemistry. 52, 477-87
(2013) Structural and mechanistic studies on ThiO, a glycine oxidase essential for thiamin biosynthesis in Bacillus subtilis. Biochemistry. 42, 2971-81
(2003) Structural Basis for Iron-Mediated Sulfur Transfer in Archael and Yeast Thiazole Synthases. Biochemistry. 55, 1826-38
(2016) Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II. Biochemistry. 44, 2319-29
(2005) Structural insights into the mechanism of the PLP synthase holoenzyme from Thermotoga maritima. Biochemistry. 45, 14609-20
(2006) Structural similarities between thiamin-binding protein and thiaminase-I suggest a common ancestor. Biochemistry. 47, 1346-57
(2008) Structural studies of thiamin monophosphate kinase in complex with substrates and products. Biochemistry. 47, 3810-21
(2008) Structural studies on 3-hydroxyanthranilate-3,4-dioxygenase: the catalytic mechanism of a complex oxidation involved in NAD biosynthesis. Biochemistry. 44, 7632-43
(2005) Structure determination and characterization of the vitamin B6 degradative enzyme (E)-2-(acetamidomethylene)succinate hydrolase. Biochemistry. 49, 1226-35
(2010) Structure of a Clostridium botulinum C143S thiaminase I/thiamin complex reveals active site architecture . Biochemistry. 52, 7830-9
(2013)