Publications
Found 51 results
Filters: Author is Kurinov, Igor [Clear All Filters]
Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation. Nat Struct Mol Biol. 21, 771-7
(2014) A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases. Structure. 10.1016/j.str.2018.06.004
(2018) Structure of human ADP-ribosyl-acceptor hydrolase 3 bound to ADP-ribose reveals a conformational switch that enables specific substrate recognition. J Biol Chem. 293, 12350-12359
(2018) Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism. Structure. 21, 1030-41
(2013) Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors. Nat Commun. 5, 4202
(2014) Structural mechanism of ligand activation in human calcium-sensing receptor. Elife. 10.7554/eLife.13662
(2016) Structural Insights into the Induced-fit Inhibition of Fascin by a Small-Molecule Inhibitor. J Mol Biol. 10.1016/j.jmb.2018.03.009
(2018) Structural diversity of the active N-terminal kinase domain of p90 ribosomal S6 kinase 2. PLoS One. 4, e8044
(2009) Structural basis for the recruitment of glycogen synthase by glycogenin. Proc Natl Acad Sci U S A. 111, E2831-40
(2014) Structural basis for auxiliary subunit KCTD16 regulation of the GABA receptor. Proc Natl Acad Sci U S A. 116, 8370-8379
(2019) Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment. Structure. 26, 1101-1115.e6
(2018) Structural and functional validation of a highly specific Smurf2 inhibitor. Protein Sci. 10.1002/pro.4885
(2023) (2021) A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases. Nat Struct Mol Biol. 18, 947-9
(2011) Rigidification Dramatically Improves Inhibitor Selectivity for RAF Kinases. ACS Med Chem Lett. 10, 1074-1080
(2019) Regulation of Protein Interactions by Mps One Binder (MOB1) Phosphorylation. Mol Cell Proteomics. 16, 1111-1125
(2017) Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system. Nucleic Acids Res. 41, 6332-46
(2013) Panel of Engineered Ubiquitin Variants Targeting the Family of Human Ubiquitin Interacting Motifs. ACS Chem Biol. 17, 941-956
(2022) Norathyriol suppresses skin cancers induced by solar ultraviolet radiation by targeting ERK kinases. Cancer Res. 72, 260-70
(2012) Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures. Nat Struct Mol Biol. 19, 1242-9
(2012) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. Award Winners and Abstracts of the 33rd Annual Symposium of The Protein Society; Seattle, Washington, June 30-July 3, 2019. 28, 12-211
(2019) (2016) (2022) MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway. Mol Cell Proteomics. 16, 1098-1110
(2017) MEK drives BRAF activation through allosteric control of KSR proteins. Nature. 10.1038/nature25478
(2018)