Publications
Chemical logic of MraY inhibition by antibacterial nucleoside natural products. Nat Commun. 10, 2917
(2019) Conformational plasticity in the selectivity filter of the TRPV2 ion channel. Nat Struct Mol Biol. 25, 405-415
(2018) Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4 Å.. Nature. 483, 489-93
(2012) Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis. Science. 341, 1012-1016
(2013) Crystal structure of the MOP flippase MurJ in an inward-facing conformation. Nat Struct Mol Biol. 24, 171-176
(2017) Crystal structure of the ternary complex of a NaV C-terminal domain, a fibroblast growth factor homologous factor, and calmodulin. Structure. 20, 1167-76
(2012) Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief. Nat Commun. 15, 10738
(2024) GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation. Nat Struct Mol Biol. 10.1038/s41594-018-0031-y
(2018) Structural analyses of Ca²⁺/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation.. Nat Commun. 5, 4896
(2014) Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. Elife. 3, e03604
(2014) Structural insights into inhibition of lipid I production in bacterial cell wall synthesis. Nature. 533, 557-560
(2016) Structures of human ENT1 in complex with adenosine reuptake inhibitors. Nat Struct Mol Biol. 26, 599-606
(2019) Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY. Nat Commun. 13, 7575
(2022) (2019) (2017)