Publications
(2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. Award Winners and Abstracts of the 32nd Annual Symposium of The Protein Society; Boston, MA, July 9-12, 2018. 27 Suppl 1, 11-245
(2017) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. Award Winners and Abstracts of the 31st Annual Symposium of The Protein Society, Montreal, Canada, July 24-27, 2017. 26, 6-209
(2019) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. Award Winners and Abstracts of the 33rd Annual Symposium of The Protein Society; Seattle, Washington, June 30-July 3, 2019. 28, 12-211
(2013) Attachment site recognition and regulation of directionality by the serine integrases. Nucleic Acids Res. 41, 8341-56
(2017) A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding. Sci Rep. 7, 7438
(2018) Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass. Nat Biotechnol. 10.1038/nbt.4153
(2013) Crystal structure of a human prion protein fragment reveals a motif for oligomer formation. J Am Chem Soc. 135, 10202-5
(2019) The crystal structure of glucokinase from Leishmania braziliensis. Mol Biochem Parasitol. 227, 47-52
(2017) Crystal Structure of the Receptor-Binding Domain of Botulinum Neurotoxin Type HA, Also Known as Type FA or H. Toxins (Basel). 10.3390/toxins9030093
(2023) Crystal structures of OrfX1, OrfX2 and the OrfX1-OrfX3 complex from the orfX gene cluster of botulinum neurotoxin E1. FEBS Lett. 597, 524-537
(2014) High-resolution crystal structure of HA33 of botulinum neurotoxin type B progenitor toxin complex. Biochem Biophys Res Commun. 446, 568-73
(2010) HMP binding protein ThiY and HMP-P synthase THI5 are structural homologues. Biochemistry. 49, 8929-36
(2017) The hypothetical protein P47 of Clostridium botulinum E1 strain Beluga has a structural topology similar to bactericidal/permeability-increasing protein. Toxicon. 10.1016/j.toxicon.2017.10.012
(2015) Identification of Non-nucleoside Human Ribonucleotide Reductase Modulators. J Med Chem. 58, 9498-509
(2015) Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics. Toxicon. 107, 43-9
(2023) Ligand bound structure of a 6-hydroxynicotinic acid 3-monooxygenase provides mechanistic insights. Arch Biochem Biophys. 752, 109859
(2014) Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex. Science. 344, 1405-10
(2022) Neutralizing epitopes on toxin A revealed by the structures of two camelid VHH antibodies. Front Immunol. 13, 978858
(2016) N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A. Nat Struct Mol Biol. 23, 656-62
(2018) Northeastern Collaborative Access Team (NE-CAT) crystallography beamlines for challenging structural biology research. Acta Crystallographica Section A Foundations and Advances. 74, a97-a97
(2022) Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies. PLoS Pathog. 18, e1010169
(2024) An RNA aptamer exploits exosite-dependent allostery to achieve specific inhibition of coagulation factor IXa. Proc Natl Acad Sci U S A. 121, e2401136121
(2021) ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes. Cell Rep. 37, 109834
(2018) Structural and biochemical characterization of the protease domain of the mosaic botulinum neurotoxin type HA. Pathog Dis. 10.1093/femspd/fty044