Army-developed Vaccine Induces Potent Zika and Dengue Cross-neutralizing Antibodies

The structures of multiple antibodies, MZ1, MZ4, and MZ24 Fab, help show that a single-dose immunization of ZIKV purified inactivated vaccine (ZPIV) in a dengue virus (DENV)-experienced human elicited potent cross-neutralizing antibodies to both ZIKV and DENV.  Data collection was performed at multiple APS MX beamlines including NE-CAT and this research is now featured on the APS website.

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