NAS Award in Molecular Biology recognizes work on innate immunity
The lab of Philip Kranzusch, Professor of Microbiology at Harvard Medical School and the Dana-Farber Cancer Institute, regularly uses beamtime at NE-CAT to examine the question of innate immunity.
Data Collection and Processing Bootcamp, April 2026
NE-CAT is offering a two-day Data Collection and Processing Bootcamp at the Advanced Photon Source in Lemont, Illinois on April 8-9, 2026. Registration priority will be given to participants who have crystals or anticipate having crystals by the course date as the focus of the bootcamp will be on data collection and processing best practice. Participants must be registered users of the APS.
Engineering llama antibodies for oral administration
Work by the pharmaceutical company, Genentech, an associate member of NE-CAT, on therapeutic nanobodies was recently featured as a Science Highlight by the APS.
Novel antibiotic overcomes drug-resistant bacteria

Work by one of our most frequent users, the Polikanov lab at the University of Illinois Chicago on antibiotics that inhibit the bacterial ribosome was featured by the APS as a Science Highlight.
Evolving Role of Macromolecular Crystallography (MX) in Structural Biology
APS (NECAT) – NSLS-II (CBMS) – SLAC (LCLS/SSRL) Joint Workshop
Theme: The Evolving Role of Macromolecular Crystallography (MX) in Structural Biology
Date: September 26, 2025
Location: SLAC National Accelerator Laboratory
Organizers: Narayanasami Sukumar, Vivian Stojanoff, Sebastien Boutet
Co-Organizer: James Baxter
New Associate Director
NE-CAT is thrilled to welcome Dr. Graeme Winter as our new Associate Director. Coming from Diamond Light Source, where he served as a Principal Scientist and Team Leader, Graeme brings a wealth of experience in synchrotron X-ray sources, crystallographic software development, and automation. During his time at Diamond Light Source, Graeme led key initiatives to improve data processing workflows and enhance beamline efficiency. He holds a Master's in Mathematics from the University of Cambridge and a Ph.D.
APS Enables Protein Design
Work by David Baker's lab on protein design which used NE-CAT for structural verification and was published in Science, is now featured on the Argonne National Laboratory website.
NE-CAT is open to General Users!
It has been a long time coming, but we are happy to announce that we are now open for General User Operations on 24-ID-E!
We will be open to users starting March 11th. For the first two weeks we will be scheduling full days. Starting March 25th, we will move back to 2 shifts (Short - 11am - 7pmCT and Long - 7pm - 9am CT).
Emails moved to cornell.edu
- Frank Murphy - frankvmurphy@cornell.edu
- Malcolm Capel - mc329@cornell.edu
- Ali Kaya - ali.kaya@cornell.edu
Let there be Data!
Two of the major milestones in commissioning a beamline have been achieved on 24-ID-E at NE-CAT. On August 9, 2024, x-rays were delivered by the APS through the Sector 24 front end. Using an ultrasensitive camera focused through a port of the monochromator, APS physicists detected the beam on the monochromator silicon crystals of both 24-ID-C and 24-ID-E. Though the focus was rough, NE-CAT was able to observe the beam. After the September shutdown, Dr. Malcolm Capel was able to carefully steer the beam through the experimental hutches to the sample position over the next two months.
Inside the awe-inspiring ‘Aurora’ supercomputer at Argonne National Lab
Read the story at WGN or watch to find one of the NE-CAT staff members.
Structure Prediction Awarded Nobel Prize
Crystallography Workshop
Hurray for Beam!
The Advanced Photon Source has begun commissioning the new storage ring and as of Thursday, April 12, there is beam in the first few meters of the storage ring. To see the most recent updates by the Advanced Photon Source, check out the Upgrade website.









