Publications
(2010) Structural basis for the coupling between activation and inactivation gates in K(+) channels. Nature. 466, 272-5
(2010) The structural basis of Cryptosporidium -specific IMP dehydrogenase inhibitor selectivity. J Am Chem Soc. 132, 1230-1
(2010) Structural insights into RNA recognition by the alternate-splicing regulator CUG-binding protein 1. Structure. 18, 1364-77
(2010) Structure of coatomer cage proteins and the relationship among COPI, COPII, and clathrin vesicle coats. Cell. 142, 123-32
(2010) Structure of the PTEN-like region of auxilin, a detector of clathrin-coated vesicle budding. Structure. 18, 1191-8
(2010) Structure-based analysis of Toxoplasma gondii profilin: a parasite-specific motif is required for recognition by Toll-like receptor 11. J Mol Biol. 403, 616-29
(2010) Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function . Biochemistry. 49, 5048-56
(2010) The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome. Nat Struct Mol Biol. 17, 289-93
(2010) A synthetic coiled-coil interactome provides heterospecific modules for molecular engineering. J Am Chem Soc. 132, 6025-31
(2009) Crystal structure and association behaviour of the GluR2 amino-terminal domain. EMBO J. 28, 1812-23
(2009) Crystal structure and association behaviour of the GluR2 amino-terminal domain. EMBO J. 28, 1812-23
(2009) Crystal structure of (+)-delta-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis. Biochemistry. 48, 6175-83
(2009) Crystal structure of (+)-delta-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis. Biochemistry. 48, 6175-83
(2009) Crystal structure of the ATP-gated P2X(4) ion channel in the closed state. Nature. 460, 592-8
(2009) Directed evolution and structural characterization of a simvastatin synthase. Chem Biol. 16, 1064-74
(2009) Effects of S1 cleavage on the structure, surface export, and signaling activity of human Notch1 and Notch2. PLoS One. 4, e6613
(2009) How to switch off a histidine kinase: crystal structure of Geobacillus stearothermophilus KinB with the inhibitor Sda. J Mol Biol. 386, 163-77
(2009) Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases. Structure. 17, 725-36

