Publications
(2009) Directed evolution and structural characterization of a simvastatin synthase. Chem Biol. 16, 1064-74
(2011) Structural and biochemical characterization of the salicylyl-acyltranferase SsfX3 from a tetracycline biosynthetic pathway. J Biol Chem. 286, 41539-51
(2013) Uncovering the enzymes that catalyze the final steps in oxytetracycline biosynthesis. J Am Chem Soc. 135, 7138-41
(2014) The role of distant mutations and allosteric regulation on LovD active site dynamics. Nat Chem Biol. 10, 431-6
(2015) Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis. J Am Chem Soc. 137, 9885-93
(2015) Origins of stereoselectivity in evolved ketoreductases. Proc Natl Acad Sci U S A. 112, E7065-72
(2022) Structure of the Repurposed Fungal Terpene Cyclase FlvF Implicated in the C-N Bond-Forming Reaction of Flavunoidine Biosynthesis. Biochemistry. 10.1021/acs.biochem.2c00335

