Publications

Found 1282 results
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2014
Spicer, T. P., Jiang, J., Taylor, A. B., Choi, J. Yong, P Hart, J., Roush, W. R., Fields, G. B., Hodder, P. S., and Minond, D. (2014) Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro. J Med Chem. 57, 9598-611
Leettola, C. N., Knight, M. Jane, Cascio, D., Hoffman, S., and Bowie, J. U. (2014) Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3. BMC Struct Biol. 14, 17
Cavalier, M. C., Pierce, A. D., Wilder, P. T., Alasady, M. J., Hartman, K. G., Neau, D. B., Foley, T. L., Jadhav, A., Maloney, D. J., Simeonov, A., Toth, E. A., and Weber, D. J. (2014) Covalent small molecule inhibitors of Ca(2+)-bound S100B. Biochemistry. 53, 6628-40
McGinty, R. K., Henrici, R. C., and Tan, S. (2014) Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome. Nature. 514, 591-6
Chen, W., Zhang, L., Zheng, G., Fu, Y., Ji, Q., Liu, F., Chen, H., and He, C. (2014) Crystal structure of the RNA demethylase ALKBH5 from zebrafish. FEBS Lett. 588, 892-8
Zhang, Z., Liu, Q., and Hendrickson, W. A. (2014) Crystal structures of apparent saccharide sensors from histidine kinase receptors prevalent in a human gut symbiont. FEBS J. 281, 4263-79
Setser, J. W., Heemstra, J. R., Walsh, C. T., and Drennan, C. L. (2014) Crystallographic evidence of drastic conformational changes in the active site of a flavin-dependent N-hydroxylase. Biochemistry. 53, 6063-77
Joh, N. H., Wang, T., Bhate, M. P., Acharya, R., Wu, Y., Grabe, M., Hong, M., Grigoryan, G., and DeGrado, W. F. (2014) De novo design of a transmembrane Zn²⁺-transporting four-helix bundle.. Science. 346, 1520-4
Huang, H., Zeqiraj, E., Dong, B., Jha, B. Kant, Duffy, N. M., Orlicky, S., Thevakumaran, N., Talukdar, M., Pillon, M. C., Ceccarelli, D. F., Wan, L. C. K., Juang, Y. - C., Mao, D. Y. L., Gaughan, C., Brinton, M. A., Perelygin, A. A., Kourinov, I., Guarné, A., Silverman, R. H., and Sicheri, F. (2014) Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity. Mol Cell. 53, 221-34
Yasui, N., Findlay, G. M., Gish, G. D., Hsiung, M. S., Huang, J., Tucholska, M., Taylor, L., Smith, L., W Boldridge, C., Koide, A., Pawson, T., and Koide, S. (2014) Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation. Mol Cell. 54, 1034-41
Yasui, N., Findlay, G. M., Gish, G. D., Hsiung, M. S., Huang, J., Tucholska, M., Taylor, L., Smith, L., W Boldridge, C., Koide, A., Pawson, T., and Koide, S. (2014) Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation. Mol Cell. 54, 1034-41
Ferreira-Cerca, S., Kiburu, I., Thomson, E., LaRonde, N., and Hurt, E. (2014) Dominant Rio1 kinase/ATPase catalytic mutant induces trapping of late pre-40S biogenesis factors in 80S-like ribosomes. Nucleic Acids Res. 42, 8635-47
Huang, H., Ceccarelli, D. F., Orlicky, S., St-Cyr, D. J., Ziemba, A., Garg, P., Plamondon, S., Auer, M., Sidhu, S., Marinier, A., Kleiger, G., Tyers, M., and Sicheri, F. (2014) E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin. Nat Chem Biol. 10, 156-163
Goldgur, Y., Susi, P., Karelehto, E., Sanmark, H., Lamminmäki, U., Oricchio, E., Wendel, H. - G., Nikolov, D. B., and Himanen, J. P. (2014) Generation and characterization of a single-chain anti-EphA2 antibody. Growth Factors. 32, 214-22
Huang, H., Suslov, N. B., Li, N. - S., Shelke, S. A., Evans, M. E., Koldobskaya, Y., Rice, P. A., and Piccirilli, J. A. (2014) A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat Chem Biol. 10, 686-91
Chen, C., Ha, B. Hak, Thévenin, A. F., Lou, H. Jane, Zhang, R., Yip, K. Y., Peterson, J. R., Gerstein, M., Kim, P. M., Filippakopoulos, P., Knapp, S., Boggon, T. J., and Turk, B. E. (2014) Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity. Mol Cell. 53, 140-7
Horenkamp, F. A., Mukherjee, S., Alix, E., Schauder, C. M., Hubber, A. M., Roy, C. R., and Reinisch, K. M. (2014) Legionella pneumophila subversion of host vesicular transport by SidC effector proteins. Traffic. 15, 488-99
Horenkamp, F. A., Mukherjee, S., Alix, E., Schauder, C. M., Hubber, A. M., Roy, C. R., and Reinisch, K. M. (2014) Legionella pneumophila subversion of host vesicular transport by SidC effector proteins. Traffic. 15, 488-99
Du, J., Johnson, L. M., Groth, M., Feng, S., Hale, C. J., Li, S., Vashisht, A. A., Wohlschlegel, J. A., Patel, D. J., and Jacobsen, S. E. (2014) Mechanism of DNA methylation-directed histone methylation by KRYPTONITE. Mol Cell. 55, 495-504
Grossmann, N., Vakkasoglu, A. S., Hulpke, S., Abele, R., Gaudet, R., and Tampé, R. (2014) Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter. Nat Commun. 5, 5419
Albright, R. A., Ornstein, D. L., Cao, W., Chang, W. C., Robert, D., Tehan, M., Hoyer, D., Liu, L., Stabach, P., Yang, G., De La Cruz, E. M., and Braddock, D. T. (2014) Molecular basis of purinergic signal metabolism by ectonucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke. J Biol Chem. 289, 3294-306
Poor, C. B., Wegner, S. V., Li, H., Dlouhy, A. C., Schuermann, J. P., Sanishvili, R., Hinshaw, J. R., Riggs-Gelasco, P. J., Outten, C. E., and He, C. (2014) Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2. Proc Natl Acad Sci U S A. 111, 4043-8
Poor, C. B., Wegner, S. V., Li, H., Dlouhy, A. C., Schuermann, J. P., Sanishvili, R., Hinshaw, J. R., Riggs-Gelasco, P. J., Outten, C. E., and He, C. (2014) Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2. Proc Natl Acad Sci U S A. 111, 4043-8
Zhong, X., Du, J., Hale, C. J., Gallego-Bartolome, J., Feng, S., Vashisht, A. A., Chory, J., Wohlschlegel, J. A., Patel, D. J., and Jacobsen, S. E. (2014) Molecular mechanism of action of plant DRM de novo DNA methyltransferases. Cell. 157, 1050-60
Xu, K., Wu, Z., Renier, N., Antipenko, A., Tzvetkova-Robev, D., Xu, Y., Minchenko, M., Nardi-Dei, V., Rajashankar, K. R., Himanen, J., Tessier-Lavigne, M., and Nikolov, D. B. (2014) Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism. Science. 344, 1275-9

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