Publications
Structure of the metal-dependent deacetylase LpxC from Yersinia enterocolitica complexed with the potent inhibitor CHIR-090 . Biochemistry. 50, 258-65
(2011) (2016) Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport. Nature. 569, 141-145
(2019) Chemical and structural investigation of the paroxetine-human serotonin transporter complex. Elife. 10.7554/eLife.56427
(2020) The Heme-Lys Cross-Link in Cytochrome P460 Promotes Catalysis by Enforcing Secondary Coordination Sphere Architecture. Biochemistry. 59, 2289-2298
(2020) Structural basis for recognition of diverse antidepressants by the human serotonin transporter. Nat Struct Mol Biol. 10.1038/s41594-018-0026-8
(2018) (2011) (2016) High-efficiency recombinant protein purification using mCherry and YFP nanobody affinity matrices. Protein Sci. 31, e4383
(2022) Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms. Proc Natl Acad Sci U S A. 110, E202-11
(2013) Structure of the infectious salmon anemia virus receptor complex illustrates a unique binding strategy for attachment. Proc Natl Acad Sci U S A. 114, E2929-E2936
(2017) Structural basis for membrane anchoring and fusion regulation of the herpes simplex virus fusogen gB. Nat Struct Mol Biol. 25, 416-424
(2018) Structural determinants of adhesion by Protocadherin-19 and implications for its role in epilepsy. Elife. 10.7554/eLife.18529
(2016) The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments. Cell. 142, 556-67
(2010) (2012) (2010) Metal-organic frameworks incorporating copper-complexed rotaxanes. Angew Chem Int Ed Engl. 51, 2160-3
(2012) Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins. Neuron. 100, 1385-1400.e6
(2018) Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states. Biochemistry. 49, 6165-76
(2010) MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway. Mol Cell Proteomics. 16, 1098-1110
(2017) (2023) Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1. J Biol Chem. 287, 24916-28
(2012) Crystal structure of heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB2) and the inhibitory influence of citrate on substrate binding. Proteins. 85, 117-124
(2017) Structural insight into the mechanisms of transport across the Salmonella enterica Pdu microcompartment shell. J Biol Chem. 285, 37838-46
(2010) Structural analysis of different LINC complexes reveals distinct binding modes. J Mol Biol. 10.1016/j.jmb.2020.09.019
(2020)