Advances in COVID-19 Prevention and Treatment Enabled by Structural Biology Research

The emergence of the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) -- the etiologic agent responsible for the current outbreak of COVID-19 -- mobilized research communities around the world to investigate the virus and the disease at unprecedented speed. To deliver information suitable for the development of vaccines, therapeutics, and diagnostics, researchers representing multiple disciplines and institutions quickly initiated broad collaborations, while DOE user facilities provided unlimited access to resources necessary for this research. As of November 16, the Advanced Photon Source has been at the forefront of structural biology work, delivering over ~10,000 hours of the beamtime, supporting over 75 teams of researchers, and delivering 95 novel structures.
Broadly, the workshop will present areas where structural biology research, including macromolecular crystallography and cryoelectron microscopy, intersects with in vivo, in vitro, and in silico studies of SARS-CoV-2 and COVID-19.  More precisely, the topics will include (a) viral biology, (b) vaccine, therapeutic, and diagnostic antibody studies, and (c) small-molecule drug discovery as it relates to viral proteases and other viral proteins. In addition, as this year’s events emphasize the need for a coordinated, long-term strategy to prevent future pandemics of zoonotic origin, a broader One Health perspective on viral pathogens will be presented.
This workshop is hosted by Michael Becker (GM/CA), Karolina Michalska (SBC-CAT), and Kay Perry (NE-CAT).  It is part of the Virtual APS/CNM User's Meeting and will be held from 10AM - 3PM Central Time on May 11 and May 12, 2021.  To attend the workshop, register (for free) for the APS User's Meeting and choose WK #9.  This is a 2-day workshop.  You must select each session separately.
Registration for the Virtual APS User's Meeting is now open.  The deadline to register for the meeting is April 19, 2021. has been extended to April 23, 2021.
PDF icon Agenda and Schedule of Speakers118.79 KB