Publications
(2013) X-ray analysis of butirosin biosynthetic enzyme BtrN redefines structural motifs for AdoMet radical chemistry. Proc Natl Acad Sci U S A. 110, 15949-54
(2017) A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases. Elife. 10.7554/eLife.26111
(2019) A widely distributed diheme enzyme from Burkholderia that displays an atypically stable bis-Fe(IV) state. Nat Commun. 10, 1101
(2025) Why Sulfur is Important in Lincosamide Antibiotics. Chem. 10.1016/j.chempr.2025.102480
(2020) Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?. Int J Parasitol Drugs Drug Resist. 13, 8-15
(2021) Whole Cell Active Inhibitors of Mycobacterial Lipoamide Dehydrogenase Afford Selectivity over the Human Enzyme through Tight Binding Interactions. ACS Infect Dis. 7, 435-444
(2014) Weak data do not make a free lunch, only a cheap meal. Acta Crystallogr D Biol Crystallogr. 70, 253-60
(2022) Watson-Crick Base-Pairing Requirements for ssDNA Recognition and Processing in Replication-Initiating HUH Endonucleases. mBio. 10.1128/mbio.02587-22
(2015) Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets. Elife. 10.7554/eLife.07646
(2017) Warfarin traps human vitamin K epoxide reductase in an intermediate state during electron transfer. Nat Struct Mol Biol. 24, 69-76
(2018) VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites. J Cell Biol. 217, 3625-3639
(2022) Visualizing the gas channel of a monofunctional carbon monoxide dehydrogenase. J Inorg Biochem. 230, 111774
(2012) Visualizing the determinants of viral RNA recognition by innate immune sensor RIG-I. Structure. 20, 1983-8
(2017) Visualizing multistep elevator-like transitions of a nucleoside transporter. Nature. 545, 66-70
(2012) Visualizing molecular juggling within a B12-dependent methyltransferase complex. Nature. 484, 265-9
(2020) Visualizing group II intron dynamics between the first and second steps of splicing. Nat Commun. 11, 2837
(2025) Visualization of Covalent Intermediates and Conformational States of Proline Utilization A by X-ray Crystallography and Molecular Dynamics Simulations. J Biol Chem. 10.1016/j.jbc.2025.110532
(2019) Visualization of clustered protocadherin neuronal self-recognition complexes. Nature. 569, 280-283
(2015) Visualization of a radical B12 enzyme with its G-protein chaperone. Proc Natl Acad Sci U S A. 112, 2419-24
(2018) A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1. Nat Commun. 9, 5367

