Publications

Found 2270 results
Journal Article
Mao, D. Y. L., Neculai, D., Downey, M., Orlicky, S., Haffani, Y. Z., Ceccarelli, D. F., Ho, J. S. L., Szilard, R. K., Zhang, W., Ho, C. S., Wan, L., Fares, C., Rumpel, S., Kurinov, I., Arrowsmith, C. H., Durocher, D., and Sicheri, F. (2008) Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine. Mol Cell. 32, 259-75
Kelley, K., Knockenhauer, K. E., Kabachinski, G., and Schwartz, T. U. (2015) Atomic structure of the Y complex of the nuclear pore. Nat Struct Mol Biol. 22, 425-431
Sangwan, S., Sawaya, M. R., Murray, K. A., Hughes, M. P., and Eisenberg, D. S. (2018) Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations. Protein Sci. 10.1002/pro.3391
Krotee, P., Rodriguez, J. A., Sawaya, M. R., Cascio, D., Reyes, F. E., Shi, D., Hattne, J., Nannenga, B. L., Oskarsson, M. E., Philipp, S., Griner, S., Jiang, L., Glabe, C. G., Westermark, G. T., Gonen, T., and Eisenberg, D. S. (2017) Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity.. Elife. 10.7554/eLife.19273
Wiltzius, J. J. W., Sievers, S. A., Sawaya, M. R., and Eisenberg, D. (2009) Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process. Protein Sci. 18, 1521-30
Hughes, M. P., Sawaya, M. R., Boyer, D. R., Goldschmidt, L., Rodriguez, J. A., Cascio, D., Chong, L., Gonen, T., and Eisenberg, D. S. (2018) Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks.. Science. 359, 698-701
Guenther, E. L., Cao, Q., Trinh, H., Lu, J., Sawaya, M. R., Cascio, D., Boyer, D. R., Rodriguez, J. A., Hughes, M. P., and Eisenberg, D. S. (2018) Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat Struct Mol Biol. 10.1038/s41594-018-0064-2
Banerjee, A., Goldgur, Y., Schwer, B., and Shuman, S. (2019) Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res. 10.1093/nar/gkz1049
Lee, S., and Verdine, G. L. (2009) Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase. Proc Natl Acad Sci U S A. 106, 18497-502
Laganowsky, A., Liu, C., Sawaya, M. R., Whitelegge, J. P., Park, J., Zhao, M., Pensalfini, A., Soriaga, A. B., Landau, M., Teng, P. K., Cascio, D., Glabe, C., and Eisenberg, D. (2012) Atomic view of a toxic amyloid small oligomer. Science. 335, 1228-31
Guenther, E. L., Ge, P., Trinh, H., Sawaya, M. R., Cascio, D., Boyer, D. R., Gonen, T., Z Zhou, H., and Eisenberg, D. S. (2018) Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Nat Struct Mol Biol. 10.1038/s41594-018-0045-5
Zangerl-Plessl, E. - M., Lee, S. - J., Maksaev, G., Bernsteiner, H., Ren, F., Yuan, P., Stary-Weinzinger, A., and Nichols, C. G. (2020) Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels. J Gen Physiol. 10.1085/jgp.201912422
Zhang, Y., Kittredge, A., Ward, N., Ji, C., Chen, S., and Yang, T. (2018) ATP activates bestrophin ion channels through direct interaction. Nat Commun. 9, 3126
Cai, R., Price, I. R., Ding, F., Wu, F., Chen, T., Zhang, Y., Liu, G., Jardine, P. J., Lu, C., and Ke, A. (2019) ATP/ADP modulates gp16-pRNA conformational change in the Phi29 DNA packaging motor. Nucleic Acids Res. 10.1093/nar/gkz692
Case, B. C., Hartley, S., Osuga, M., Jeruzalmi, D., and Hingorani, M. M. (2019) The ATPase mechanism of UvrA2 reveals the distinct roles of proximal and distal ATPase sites in nucleotide excision repair. Nucleic Acids Res. 47, 4136-4152
Ferreira-Cerca, S., Sagar, V., Schäfer, T., Diop, M., Wesseling, A. - M., Lu, H., Chai, E., Hurt, E., and LaRonde-LeBlanc, N. (2012) ATPase-dependent role of the atypical kinase Rio2 on the evolving pre-40S ribosomal subunit. Nat Struct Mol Biol. 19, 1316-23
Iwase, S., Xiang, B., Ghosh, S., Ren, T., Lewis, P. W., Cochrane, J. C., C Allis, D., Picketts, D. J., Patel, D. J., Li, H., and Shi, Y. (2011) ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome. Nat Struct Mol Biol. 18, 769-76
Rutherford, K., Yuan, P., Perry, K., Sharp, R., and Van Duyne, G. D. (2013) Attachment site recognition and regulation of directionality by the serine integrases. Nucleic Acids Res. 41, 8341-56
Muok, A. R., Ortega, D. R., Kurniyati, K., Yang, W., Maschmann, Z. A., Mabrouk, A. Sidi, Li, C., Crane, B. R., and Briegel, A. (2020) Atypical chemoreceptor arrays accommodate high membrane curvature. Nat Commun. 11, 5763
G Hobbs, A., Baker, N. M., Miermont, A. M., Thurman, R. D., Pierobon, M., Tran, T. H., Anderson, A. O., Waters, A. M., J Diehl, N., Papke, B., Hodge, R. G., Klomp, J. E., Goodwin, C. M., DeLiberty, J. M., Wang, J., Ng, R. W. S., Gautam, P., Bryant, K. L., Esposito, D., Campbell, S. L., Petricoin, E. F., Simanshu, D. K., Aguirre, A. J., Wolpin, B. M., Wennerberg, K., Rudloff, U., Cox, A. D., and Der, C. J. (2019) Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer. Cancer Discov. 10.1158/2159-8290.CD-19-1006
Jobichen, C., Chong, T. Ying, Ling, T. Hui, and Sivaraman, J. (2021) The Autocatalytic Cleavage Domain Is Not Required for the Activity of ScpC, a Virulence Protease from : A Structural Insight. Biochemistry. 60, 1564-1568
Iglesias, N., Currie, M. A., Jih, G., Paulo, J. A., Siuti, N., Kalocsay, M., Gygi, S. P., and Moazed, D. (2018) Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability. Nature. 560, 504-508
Kasznel, A. J., Harris, T., Porter, N. J., Zhang, Y., and Chenoweth, D. M. (2019) Aza-proline effectively mimics l-proline stereochemistry in triple helical collagen. Chem Sci. 10, 6979-6983
Tookmanian, E. M., Phillips-Piro, C. M., Fenlon, E. E., and Brewer, S. H. (2015) Azidoethoxyphenylalanine as a Vibrational Reporter and Click Chemistry Partner in Proteins. Chemistry. 21, 19096-103
Bridwell-Rabb, J., Zhong, A., Sun, H. G., Drennan, C. L., and Liu, H. -wen (2017) A B12-dependent radical SAM enzyme involved in oxetanocin A biosynthesis. Nature. 544, 322-326

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