Publications

Found 4 results
Filters: Author is Elledge, Stephen J  [Clear All Filters]
2011
Joo, W., Xu, G., Persky, N. S., Smogorzewska, A., Rudge, D. G., Buzovetsky, O., Elledge, S. J., and Pavletich, N. P. (2011) Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway. Science. 333, 312-6
2014
Wang, R., Persky, N. S., Yoo, B., Ouerfelli, O., Smogorzewska, A., Elledge, S. J., and Pavletich, N. P. (2014) DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1. Science. 346, 1127-30
2023
Scott, D. C., King, M. T., Baek, K., Gee, C. T., Kalathur, R., Li, J., Purser, N., Nourse, A., Chai, S. C., Vaithiyalingam, S., Chen, T., Lee, R. E., Elledge, S. J., Kleiger, G., and Schulman, B. A. (2023) E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity. Mol Cell. 83, 770-786.e9
2024
Scott, D. C., Dharuman, S., Griffith, E., Chai, S. C., Ronnebaum, J., King, M. T., Tangallapally, R., Lee, C., Gee, C. T., Yang, L., Li, Y., Loudon, V. C., Lee, H. Won, Ochoada, J., Miller, D. J., Jayasinghe, T., Paulo, J. A., Elledge, S. J., J Harper, W., Chen, T., Lee, R. E., and Schulman, B. A. (2024) Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2. Nat Commun. 15, 8829