Publications
Peptide Centric Vβ Specific Germline Contacts Shape a Specialist T Cell Response.. Front Immunol. 13, 847092
(2022) Structural insights into glutathione-mediated activation of the master regulator PrfA in Listeria monocytogenes. Protein Cell. 8, 308-312
(2017) Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell. 141, 1183-94
(2010) REV7 has a dynamic adaptor region to accommodate small GTPase RAN/Shigella IpaB ligands and its activity is regulated by RanGTP/GDP switch.. J Biol Chem. 10.1074/jbc.RA119.010123
(2019) (2009) (2019) Diamonds in the rough: a strong case for the inclusion of weak-intensity X-ray diffraction data. Acta Crystallogr D Biol Crystallogr. 70, 1491-7
(2014) Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4). J Biol Chem. 10.1074/jbc.RA118.005428
(2019) Crystal structure of human IRAK1. Proc Natl Acad Sci U S A. 10.1073/pnas.1714386114
(2017) Insights into base selectivity from the 1.8 Å resolution structure of an RB69 DNA polymerase ternary complex.. Biochemistry. 50, 581-90
(2011) Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature. 503, 141-5
(2013) Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context. Nat Struct Mol Biol. 19, 212-9
(2012) Acute pharmacological degradation of Helios destabilizes regulatory T cells. Nat Chem Biol. 17, 711-717
(2021) (2008) Programming A Molecular Relay for Ultrasensitive Biodetection through (129)Xe NMR.. Angew Chem Int Ed Engl. 55, 1733-6
(2016) The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations. Nat Struct Mol Biol. 17, 1324-9
(2010) Etesevimab in combination with JS026 neutralizing SARS-CoV-2 and its variants. Emerg Microbes Infect. 11, 548-551
(2022) Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains. ACS Chem Biol. 10.1021/acschembio.7b00638
(2018) Observation of time-resolved structural changes by linear interpolation of highly redundant X-ray diffraction data. Acta Crystallogr D Biol Crystallogr. 60, 1579-85
(2004) Crystallographic analysis of TPP riboswitch binding by small-molecule ligands discovered through fragment-based drug discovery approaches. Methods Enzymol. 549, 221-33
(2014) Structural basis for activity of highly efficient RNA mimics of green fluorescent protein. Nat Struct Mol Biol. 21, 658-63
(2014) A homodimer interface without base pairs in an RNA mimic of red fluorescent protein. Nat Chem Biol. 13, 1195-1201
(2017) Validating fragment-based drug discovery for biological RNAs: lead fragments bind and remodel the TPP riboswitch specifically. Chem Biol. 21, 591-5
(2014) Structural basis for the specificity of PPM1H phosphatase for Rab GTPases. EMBO Rep. 10.15252/embr.202152675
(2021) Dual arginine recognition of LRRK2 phosphorylated Rab GTPases. Biophys J. 10.1016/j.bpj.2021.03.030
(2021)