Publications

Found 2714 results
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2025
Liu, B. Hui, Liu, M., Radhakrishnan, S., Dai, M. - Y., Jaladanki, C. Kumar, Gao, C., Tang, J. Ping, Kumari, K., Go, M. Lin, Vu, K. Anh L., Kwon, J., Seo, H. - S., Song, K., Tian, X., Feng, L., Tan, J. L., Melkonian, A. V., Liu, Z., Wulf, G., Arthanari, H., Qi, J., Dhe-Paganon, S., Clohessy, J. G., Choong, Y. Khai, Sivaraman, J., Fan, H., Tenen, D. G., and Chai, L. (2025) Targeting transcription factors through an IMiD independent zinc finger domain. EMBO Mol Med. 17, 1393-1416
Sabonis, D., Avraham, C., Chang, R. B., Lu, A., Herbst, E., Silanskas, A., Vilutis, D., Leavitt, A., Yirmiya, E., Toyoda, H. C., Ruksenaite, A., Zaremba, M., Osterman, I., Amitai, G., Kranzusch, P. J., Sorek, R., and Tamulaitiene, G. (2025) TIR domains produce histidine-ADPR as an immune signal in bacteria. Nature. 642, 467-473
Sabonis, D., Avraham, C., Chang, R. B., Lu, A., Herbst, E., Silanskas, A., Vilutis, D., Leavitt, A., Yirmiya, E., Toyoda, H. C., Ruksenaite, A., Zaremba, M., Osterman, I., Amitai, G., Kranzusch, P. J., Sorek, R., and Tamulaitiene, G. (2025) TIR domains produce histidine-ADPR as an immune signal in bacteria. Nature. 642, 467-473
Sabonis, D., Avraham, C., Chang, R. B., Lu, A., Herbst, E., Silanskas, A., Vilutis, D., Leavitt, A., Yirmiya, E., Toyoda, H. C., Ruksenaite, A., Zaremba, M., Osterman, I., Amitai, G., Kranzusch, P. J., Sorek, R., and Tamulaitiene, G. (2025) TIR domains produce histidine-ADPR as an immune signal in bacteria. Nature. 642, 467-473
Kubeš, J., Karabanovich, G., Cong, A. T. Q., Melnikova, I., Lenčová, O., Kollárová, P., Piskáčková, H. Bavlovič, Keresteš, V., Applová, L., Arrouye, L. C. M., Alvey, J. R., Paluncic, J., Witter, T. L., Jirkovská, A., Kuneš, J., Štěrbová-Kovaříková, P., Austin, C. A., Štěrba, M., Šimůnek, T., Roh, J., and Schellenberg, M. J. (2025) Topobexin targets the Topoisomerase II ATPase domain for beta isoform-selective inhibition and anthracycline cardioprotection. Nat Commun. 16, 4928
Kubeš, J., Karabanovich, G., Cong, A. T. Q., Melnikova, I., Lenčová, O., Kollárová, P., Piskáčková, H. Bavlovič, Keresteš, V., Applová, L., Arrouye, L. C. M., Alvey, J. R., Paluncic, J., Witter, T. L., Jirkovská, A., Kuneš, J., Štěrbová-Kovaříková, P., Austin, C. A., Štěrba, M., Šimůnek, T., Roh, J., and Schellenberg, M. J. (2025) Topobexin targets the Topoisomerase II ATPase domain for beta isoform-selective inhibition and anthracycline cardioprotection. Nat Commun. 16, 4928
Kubeš, J., Karabanovich, G., Cong, A. T. Q., Melnikova, I., Lenčová, O., Kollárová, P., Piskáčková, H. Bavlovič, Keresteš, V., Applová, L., Arrouye, L. C. M., Alvey, J. R., Paluncic, J., Witter, T. L., Jirkovská, A., Kuneš, J., Štěrbová-Kovaříková, P., Austin, C. A., Štěrba, M., Šimůnek, T., Roh, J., and Schellenberg, M. J. (2025) Topobexin targets the Topoisomerase II ATPase domain for beta isoform-selective inhibition and anthracycline cardioprotection. Nat Commun. 16, 4928
Kubeš, J., Karabanovich, G., Cong, A. T. Q., Melnikova, I., Lenčová, O., Kollárová, P., Piskáčková, H. Bavlovič, Keresteš, V., Applová, L., Arrouye, L. C. M., Alvey, J. R., Paluncic, J., Witter, T. L., Jirkovská, A., Kuneš, J., Štěrbová-Kovaříková, P., Austin, C. A., Štěrba, M., Šimůnek, T., Roh, J., and Schellenberg, M. J. (2025) Topobexin targets the Topoisomerase II ATPase domain for beta isoform-selective inhibition and anthracycline cardioprotection. Nat Commun. 16, 4928
J Y Wu, K., Aleksandrova, E. V., Robinson, P. J., Benedetto, A. E., Yu, M., Tresco, B. I. C., N Y See, D., Jiang, T., Ramkissoon, A., Dunand, C. F., Svetlov, M. S., Lee, J., Polikanov, Y. S., and Myers, A. G. (2025) Why Sulfur is Important in Lincosamide Antibiotics. Chem. 10.1016/j.chempr.2025.102480
2024
Sidibé, A., Mykuliak, V. V., Zhang, P., Hytönen, V. P., Wu, J., and Wehrle-Haller, B. (2024) Acetyl-NPKY of integrin-β1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity.. iScience. 27, 110129
Rechkoblit, O., Sciaky, D., Kreitler, D. F., Buku, A., Kottur, J., and Aggarwal, A. K. (2024) Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides. Nat Struct Mol Biol. 10.1038/s41594-024-01220-x
Mealka, M., Sierra, N. A., Matteo, D. Avellaneda, Albekioni, E., Khoury, R., Mai, T., Conley, B. M., Coleman, N. J., Sabo, K. A., Komives, E. A., Bobkov, A. A., Cooksy, A. L., Silletti, S., Schiffer, J. M., Huxford, T., and Sohl, C. D. (2024) Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms. Nat Commun. 15, 3785
Mealka, M., Sierra, N. A., Matteo, D. Avellaneda, Albekioni, E., Khoury, R., Mai, T., Conley, B. M., Coleman, N. J., Sabo, K. A., Komives, E. A., Bobkov, A. A., Cooksy, A. L., Silletti, S., Schiffer, J. M., Huxford, T., and Sohl, C. D. (2024) Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms. Nat Commun. 15, 3785
Mealka, M., Sierra, N. A., Matteo, D. Avellaneda, Albekioni, E., Khoury, R., Mai, T., Conley, B. M., Coleman, N. J., Sabo, K. A., Komives, E. A., Bobkov, A. A., Cooksy, A. L., Silletti, S., Schiffer, J. M., Huxford, T., and Sohl, C. D. (2024) Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms. Nat Commun. 15, 3785
Mealka, M., Sierra, N. A., Matteo, D. Avellaneda, Albekioni, E., Khoury, R., Mai, T., Conley, B. M., Coleman, N. J., Sabo, K. A., Komives, E. A., Bobkov, A. A., Cooksy, A. L., Silletti, S., Schiffer, J. M., Huxford, T., and Sohl, C. D. (2024) Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms. Nat Commun. 15, 3785
Mealka, M., Sierra, N. A., Matteo, D. Avellaneda, Albekioni, E., Khoury, R., Mai, T., Conley, B. M., Coleman, N. J., Sabo, K. A., Komives, E. A., Bobkov, A. A., Cooksy, A. L., Silletti, S., Schiffer, J. M., Huxford, T., and Sohl, C. D. (2024) Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms. Nat Commun. 15, 3785
Miller, J. E., Agdanowski, M. P., Dolinsky, J. L., Sawaya, M. R., Cascio, D., Rodriguez, J. A., and Yeates, T. O. (2024) AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography. Acta Crystallogr D Struct Biol. 80, 270-278
J Y Wu, K., Tresco, B. I. C., Ramkissoon, A., Aleksandrova, E. V., Syroegin, E. A., N Y See, D., Liow, P., Dittemore, G. A., Yu, M., Testolin, G., Mitcheltree, M. J., Liu, R. Y., Svetlov, M. S., Polikanov, Y. S., and Myers, A. G. (2024) An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance. Science. 383, 721-726
J Y Wu, K., Tresco, B. I. C., Ramkissoon, A., Aleksandrova, E. V., Syroegin, E. A., N Y See, D., Liow, P., Dittemore, G. A., Yu, M., Testolin, G., Mitcheltree, M. J., Liu, R. Y., Svetlov, M. S., Polikanov, Y. S., and Myers, A. G. (2024) An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance. Science. 383, 721-726
Bruce, H. A., Singer, A. U., Blazer, L. L., Luu, K., Ploder, L., Pavlenco, A., Kurinov, I., Adams, J. J., and Sidhu, S. S. (2024) Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones. Protein Sci. 33, e5081
Bruce, H. A., Singer, A. U., Blazer, L. L., Luu, K., Ploder, L., Pavlenco, A., Kurinov, I., Adams, J. J., and Sidhu, S. S. (2024) Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones. Protein Sci. 33, e5081
Batool, Z., Pavlova, J. A., Paranjpe, M. N., Tereshchenkov, A. G., Lukianov, D. A., Osterman, I. A., Bogdanov, A. A., Sumbatyan, N. V., and Polikanov, Y. S. (2024) Berberine analog of chloramphenicol exhibits a distinct mode of action and unveils ribosome plasticity. Structure. 10.1016/j.str.2024.06.013
An, L., Said, M., Tran, L., Majumder, S., Goreshnik, I., Lee, G. Rie, Juergens, D., Dauparas, J., Anishchenko, I., Coventry, B., Bera, A. K., Kang, A., Levine, P. M., Alvarez, V., Pillai, A., Norn, C., Feldman, D., Zorine, D., Hicks, D. R., Li, X., Sanchez, M. Garcia, Vafeados, D. K., Salveson, P. J., Vorobieva, A. A., and Baker, D. (2024) Binding and sensing diverse small molecules using shape-complementary pseudocycles. Science. 385, 276-282
An, L., Said, M., Tran, L., Majumder, S., Goreshnik, I., Lee, G. Rie, Juergens, D., Dauparas, J., Anishchenko, I., Coventry, B., Bera, A. K., Kang, A., Levine, P. M., Alvarez, V., Pillai, A., Norn, C., Feldman, D., Zorine, D., Hicks, D. R., Li, X., Sanchez, M. Garcia, Vafeados, D. K., Salveson, P. J., Vorobieva, A. A., and Baker, D. (2024) Binding and sensing diverse small molecules using shape-complementary pseudocycles. Science. 385, 276-282
An, L., Said, M., Tran, L., Majumder, S., Goreshnik, I., Lee, G. Rie, Juergens, D., Dauparas, J., Anishchenko, I., Coventry, B., Bera, A. K., Kang, A., Levine, P. M., Alvarez, V., Pillai, A., Norn, C., Feldman, D., Zorine, D., Hicks, D. R., Li, X., Sanchez, M. Garcia, Vafeados, D. K., Salveson, P. J., Vorobieva, A. A., and Baker, D. (2024) Binding and sensing diverse small molecules using shape-complementary pseudocycles. Science. 385, 276-282

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