Found 12 results
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Journal Article
Gagnon, M. G., Roy, R. N., Lomakin, I. B., Florin, T., Mankin, A. S., and Steitz, T. A. (2016) Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res. 44, 2439-50
Batool, Z., Lomakin, I. B., Polikanov, Y. S., and Bunick, C. G. (2020) Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Proc Natl Acad Sci U S A. 10.1073/pnas.2008671117
Roy, R. N., Lomakin, I. B., Gagnon, M. G., and Steitz, T. A. (2015) The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin. Nat Struct Mol Biol. 22, 466-9
Wang, J., Sachpatzidis, A., Christian, T. D., Lomakin, I. B., Garen, A., and Konigsberg, W. H. (2022) Insight into the Tumor Suppression Mechanism from the Structure of Human Polypyrimidine Splicing Factor (PSF/SFPQ) Complexed with a 30mer RNA from Murine Virus-like 30S Transcript-1. Biochemistry. 61, 1723-1734
Lomakin, I. B., and Steitz, T. A. (2013) The initiation of mammalian protein synthesis and mRNA scanning mechanism. Nature. 500, 307-11
Eldirany, S. A., Ho, M., Hinbest, A. J., Lomakin, I. B., and Bunick, C. G. (2019) Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly. EMBO J. 10.15252/embj.2018100741
Lomakin, I. B., Xiong, Y., and Steitz, T. A. (2007) The crystal structure of yeast fatty acid synthase, a cellular machine with eight active sites working together. Cell. 129, 319-32
Lomakin, I. B., Stolboushkina, E. A., Vaidya, A. T., Zhao, C., Garber, M. B., Dmitriev, S. E., and Steitz, T. A. (2017) Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1. Cell Rep. 20, 521-528
Lomakin, I. B., Dmitriev, S. E., and Steitz, T. A. (2019) Crystal structure of the DENR-MCT-1 complex revealed zinc-binding site essential for heterodimer formation. Proc Natl Acad Sci U S A. 116, 528-533
Vaidya, A. T., Lomakin, I. B., Joseph, N. N., Dmitriev, S. E., and Steitz, T. A. (2017) Crystal Structure of the C-terminal Domain of Human eIF2D and its Implications on Eukaryotic Translation Initiation. J Mol Biol. 10.1016/j.jmb.2017.07.015
Lomakin, I. B., De, S., Wang, J., Borkar, A. N., and Steitz, T. A. (2020) Crystal structure of the C-terminal domain of DENR. Comput Struct Biotechnol J. 18, 696-704
Lomakin, I. B., Hinbest, A. J., Ho, M., Eldirany, S. A., and Bunick, C. G. (2020) Crystal Structure of Keratin 1/10(C401A) 2B Heterodimer Demonstrates a Proclivity for the C-Terminus of Helix 2B to Form Higher Order Molecular Contacts. Yale J Biol Med. 93, 3-17