Publications

Found 431 results
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2024
Solano, Y. J., Everett, M. P., Dang, K. S., Abueg, J., and Kiser, P. D. (2024) Carotenoid cleavage enzymes evolved convergently to generate the visual chromophore. Nat Chem Biol. 20, 779-788
Tamilselvan, E., and Sotomayor, M. (2024) CELSR1, a core planar cell polarity protein, features a weakly adhesive and flexible cadherin ectodomain. Structure. 10.1016/j.str.2024.01.003
Owens, D. D. G., Maitland, M. E. R., Yazdi, A. Khalili, Song, X., Reber, V., Schwalm, M. P., Machado, R. A. C., Bauer, N., Wang, X., Szewczyk, M. M., Dong, C., Dong, A., Loppnau, P., Calabrese, M. F., Dowling, M. S., Lee, J., Montgomery, J. I., O'Connell, T. N., Subramanyam, C., Wang, F., Adamson, E. C., Schapira, M., Gstaiger, M., Knapp, S., Vedadi, M., Min, J., Lajoie, G. A., Barsyte-Lovejoy, D., Owen, D. R., Schild-Poulter, C., and Arrowsmith, C. H. (2024) A chemical probe to modulate human GID4 Pro/N-degron interactions. Nat Chem Biol. 10.1038/s41589-024-01618-0
Maisonneuve, P., Sahmi, M., Bergeron-Labrecque, F., Ma, X. Iris, Queguiner, J., Arseneault, G., Lefrançois, M., Kurinov, I., Fronzes, R., Sicheri, F., and Therrien, M. (2024) The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction. Nat Struct Mol Biol. 10.1038/s41594-024-01233-6
Esler, M. A., Belica, C. A., Rollie, J. A., Brown, W. L., Moghadasi, S. Arad, Shi, K., Harki, D. A., Harris, R. S., and Aihara, H. (2024) A compact stem-loop DNA aptamer targets a uracil-binding pocket in the SARS-CoV-2 nucleocapsid RNA-binding domain. Nucleic Acids Res. 52, 13138-13151
Whitley, M. J., Tran, T. H., Rigby, M., Yi, M., Dharmaiah, S., Waybright, T. J., Ramakrishnan, N., Perkins, S., Taylor, T., Messing, S., Esposito, D., Nissley, D. V., McCormick, F., Stephen, A. G., Turbyville, T., Cornilescu, G., and Simanshu, D. K. (2024) Comparative analysis of KRAS4a and KRAS4b splice variants reveals distinctive structural and functional properties. Sci Adv. 10, eadj4137
Lin, D. Yin-wei, Kueffer, L. E., Juneja, P., and Wales, T. E. (2024) Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. Elife. 10.7554/eLife.89489
Kolesiński, P., McGowan, M., Botteaux, A., Smeesters, P. R., and Ghosh, P. (2024) Conservation of C4BP-binding sequence patterns in Streptococcus pyogenes M and Enn proteins. J Biol Chem. 300, 107478
Baca, C. F., Yu, Y., Rostøl, J. T., Majumder, P., Patel, D. J., and Marraffini, L. A. (2024) The CRISPR effector Cam1 mediates membrane depolarization for phage defence. Nature. 10.1038/s41586-023-06902-y
Adams, M. C., Schiltz, C. J., Sun, J., Hosford, C. J., Johnson, V. M., Pan, H., Borbat, P. P., Freed, J. H., Thomason, L. C., Court, C., Court, D. L., and Chappie, J. S. (2024) The crystal structure of bacteriophage λ RexA provides novel insights into the DNA binding properties of Rex-like phage exclusion proteins.. Nucleic Acids Res. 52, 4659-4675
Kumar, R. P., Matos, J. O., Black, B. Y., Ellenburg, W. H., Chen, J., Patterson, M. K., Gehtman, J. A., Theobald, D. L., Krauss, I. J., and Oprian, D. D. (2024) Crystal Structure of Caryolan-1-ol Synthase, a Sesquiterpene Synthase Catalyzing an Initial Anti-Markovnikov Cyclization Reaction. Biochemistry. 63, 2904-2915
Forker, K., Fleming, M. C., Pearce, K. H., Vaziri, C., Bowers, A. A., and Zhou, P. (2024) Crystal structure of MAGEA4 MHD-RAD18 R6BD reveals a flipped binding mode compared to AlphaFold2 prediction. EMBO J. 10.1038/s44318-024-00140-2
Meeks, K. R., Bogner, A. N., Nix, J. C., and Tanner, J. J. (2024) Crystallographic Fragment Screening of a Bifunctional Proline Catabolic Enzyme Reveals New Inhibitor Templates for Proline Dehydrogenase and L-Glutamate-γ-semialdehyde Dehydrogenase.. Molecules. 10.3390/molecules29225408
Li, Y., Wei, Y., Ultsch, M., Li, W., Tang, W., Tombling, B., Gao, X., Dimitrova, Y., Gampe, C., Fuhrmann, J., Zhang, Y., Hannoush, R. N., and Kirchhofer, D. (2024) Cystine-knot peptide inhibitors of HTRA1 bind to a cryptic pocket within the active site region. Nat Commun. 15, 4359

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