Publications
Geometric Lessons and Design Strategies for Nanoscale Protein Cages. ACS Nano. 10.1021/acsnano.0c07167
(2021) Genetic screen for suppression of transcriptional interference identifies a gain-of-function mutation in Pol2 termination factor Seb1. Proc Natl Acad Sci U S A. 10.1073/pnas.2108105118
(2021) Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1. RNA. 21, 1135-46
(2015) Generation of novel copper sites by mutation of the axial ligand of amicyanin. Atomic resolution structures and spectroscopic properties. Biochemistry. 46, 1900-12
(2007) Generation and molecular recognition of melanoma-associated antigen-specific human γδ T cells.. Sci Immunol. 10.1126/sciimmunol.aav4036
(2018) (2014) (2016) Gene identification and structural characterization of the pyridoxal 5'-phosphate degradative protein 3-hydroxy-2-methylpyridine-4,5-dicarboxylate decarboxylase from mesorhizobium loti MAFF303099. Biochemistry. 46, 13606-15
(2007) (2013) Gating mechanisms of acid-sensing ion channels. Nature. 10.1038/nature25782
(2018) Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 M/3CL in Living Cells. mBio. 10.1128/mbio.00784-22
(2022) (2013) A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography. Proc Natl Acad Sci U S A. 112, 4310-5
(2015) Functional Impact of a Cancer-Related Variant in Human Δ-Pyrroline-5-Carboxylate Reductase 1.. ACS Omega. 8, 3509-3519
(2023) Functional consequences of B-repeat sequence variation in the staphylococcal biofilm protein Aap: deciphering the assembly code. Biochem J. 474, 427-443
(2017) Functional characterization of a PROTAC directed against BRAF mutant V600E. Nat Chem Biol. 10.1038/s41589-020-0609-7
(2020) Functional characterization and crystal structure of thermostable amylase from Thermotoga petrophila, reveals high thermostability and an unusual form of dimerization. Biochim Biophys Acta. 1865, 1237-1245
(2017) Functional and Structural Analysis of the Toxin-Binding Site of the Cadherin G-Protein-Coupled Receptor, BT-R, for Cry1A Toxins of . Biochemistry. 61, 752-766
(2022) Functional and structural analysis of a key region of the cell wall inhibitor moenomycin. ACS Chem Biol. 5, 701-11
(2010) The function of the PduJ microcompartment shell protein is determined by the genomic position of its encoding gene. Mol Microbiol. 101, 770-83
(2016) Fully human monoclonal antibody targeting activated ADAM10 on colorectal cancer cells. Biomed Pharmacother. 161, 114494
(2023) Fully convergent chemical synthesis of ester insulin: determination of the high resolution X-ray structure by racemic protein crystallography. J Am Chem Soc. 135, 3173-85
(2013) The full-length structure of Thermus scotoductus OLD defines the ATP hydrolysis properties and catalytic mechanism of Class 1 OLD family nucleases. Nucleic Acids Res. 48, 2762-2776
(2020) (2016) (2023)