Publications

Found 21 results
Filters: Author is Verdine, Gregory L  [Clear All Filters]
Journal Article
Lee, S., and Verdine, G. L. (2009) Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase. Proc Natl Acad Sci U S A. 106, 18497-502
Pakotiprapha, D., Inuzuka, Y., Bowman, B. R., Moolenaar, G. F., Goosen, N., Jeruzalmi, D., and Verdine, G. L. (2008) Crystal structure of Bacillus stearothermophilus UvrA provides insight into ATP-modulated dimerization, UvrB interaction, and DNA binding. Mol Cell. 29, 122-33
Qi, Y., Spong, M. C., Nam, K., Banerjee, A., Jiralerspong, S., Karplus, M., and Verdine, G. L. (2009) Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme. Nature. 462, 762-6
Crenshaw, C. M., Nam, K., Oo, K., Kutchukian, P. S., Bowman, B. R., Karplus, M., and Verdine, G. L. (2012) Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1. J Biol Chem. 287, 24916-28
McGee, J. H., Shim, S. Youn, Lee, S. - J., Swanson, P. K., Jiang, Y., Durney, M. A., and Verdine, G. L. (2017) Exceptionally high-affinity Ras binders that remodel its effector domain. J Biol Chem. 10.1074/jbc.M117.816348
Ruthenburg, A. J., Wang, W., Graybosch, D. M., Li, H., C Allis, D., Patel, D. J., and Verdine, G. L. (2006) Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex. Nat Struct Mol Biol. 13, 704-12
Grossmann, T. N., Yeh, J. T. - H., Bowman, B. R., Chu, Q., Moellering, R. E., and Verdine, G. L. (2012) Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin.. Proc Natl Acad Sci U S A. 109, 17942-7
Lee, S. - J., Sung, R. - J., and Verdine, G. L. (2019) Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System. Research (Wash D C). 2019, 5641746
Wei, H., Ruthenburg, A. J., Bechis, S. K., and Verdine, G. L. (2005) Nucleotide-dependent domain movement in the ATPase domain of a human type IIA DNA topoisomerase. J Biol Chem. 280, 37041-7
Sung, R. - J., Zhang, M., Qi, Y., and Verdine, G. L. (2012) Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM. J Biol Chem. 287, 18044-54
Qi, Y., Nam, K., Spong, M. C., Banerjee, A., Sung, R. - J., Zhang, M., Karplus, M., and Verdine, G. L. (2012) Strandwise translocation of a DNA glycosylase on undamaged DNA. Proc Natl Acad Sci U S A. 109, 1086-91
Sung, R. - J., Zhang, M., Qi, Y., and Verdine, G. L. (2013) Structural and biochemical analysis of DNA helix invasion by the bacterial 8-oxoguanine DNA glycosylase MutM. J Biol Chem. 288, 10012-23
Wang, L., Lee, S. - J., and Verdine, G. L. (2015) Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase. J Biol Chem. 290, 17096-105
Wang, L., Chakravarthy, S., and Verdine, G. L. (2017) Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase. J Biol Chem. 292, 5007-5017
Pakotiprapha, D., Liu, Y., Verdine, G. L., and Jeruzalmi, D. (2009) A structural model for the damage-sensing complex in bacterial nucleotide excision repair. J Biol Chem. 284, 12837-44
Didovyk, A., and Verdine, G. L. (2012) Structural origins of DNA target selection and nucleobase extrusion by a DNA cytosine methyltransferase. J Biol Chem. 287, 40099-105
Banerjee, A., Santos, W. L., and Verdine, G. L. (2006) Structure of a DNA glycosylase searching for lesions. Science. 311, 1153-7
Bowman, B. R., Lee, S., Wang, S., and Verdine, G. L. (2010) Structure of Escherichia coli AlkA in complex with undamaged DNA. J Biol Chem. 285, 35783-91
Bowman, B. R., Lee, S., Wang, S., and Verdine, G. L. (2008) Structure of the E. coli DNA glycosylase AlkA bound to the ends of duplex DNA: a system for the structure determination of lesion-containing DNA. Structure. 16, 1166-74
Lee, S., Bowman, B. R., Ueno, Y., Wang, S., and Verdine, G. L. (2008) Synthesis and structure of duplex DNA containing the genotoxic nucleobase lesion N7-methylguanine. J Am Chem Soc. 130, 11570-1
Shigdel, U. K., Ovchinnikov, V., Lee, S. - J., Shih, J. A., Karplus, M., Nam, K., and Verdine, G. L. (2020) The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase. Nat Commun. 11, 4437