Work by the pharmaceutical company, Genentech, an associate member of NE-CAT, on therapeutic nanobodies was recently featured as a Science Highlight by the APS.

Work by one of our most frequent users, the Polikanov lab at the University of Illinois Chicago on antibiotics that inhibit the bacterial ribosome was featured by the APS as a Science Highlight.

The Fall Shutdown of the APS for Maintenance will begin August 7 and end September 8. During this time, electrical work at the APS will necessitate power shutdowns on Saturdays, August 9, 6am to 6pm and August 23, 6am to 6pm.  Be advised, RAPD2, Remote, Data transfer via sync script or Globus will be unavailable from Friday, August 8 through Monday, August 11.  

APS (NECAT) – NSLS-II (CBMS) – SLAC (LCLS/SSRL) Joint Workshop

Theme: The Evolving Role of Macromolecular Crystallography (MX) in Structural Biology

Date: September 26, 2025

Location: SLAC National Accelerator Laboratory

Organizers: Narayanasami Sukumar, Vivian Stojanoff, Sebastien Boutet

Co-Organizer: James Baxter

NE-CAT is pleased to offer a two-day Data Collection and Processing Bootcamp at the Advanced Photon Source, July 24-25, 2025.

NE-CAT is thrilled to welcome Dr. Graeme Winter as our new Associate Director. Coming from Diamond Light Source, where he served as a Principal Scientist and Team Leader, Graeme brings a wealth of experience in synchrotron X-ray sources, crystallographic software development, and automation. During his time at Diamond Light Source, Graeme led key initiatives to improve data processing workflows and enhance beamline efficiency. He holds a Master's in Mathematics from the University of Cambridge and a Ph.D.

Work by David Baker's lab on protein design which used NE-CAT for structural verification and was published in Science, is now featured on the Argonne National Laboratory website.

It has been a long time coming, but we are happy to announce that we are now open for General User Operations on 24-ID-E! 

We will be open to users starting March 11th.  For the first two weeks we will be scheduling full days.  Starting March 25th, we will move back to 2 shifts (Short - 11am - 7pmCT and Long - 7pm - 9am CT).  

• Frank Murphy - frankvmurphy@cornell.edu
• Malcolm Capel - mc329@cornell.edu
• Ali Kaya - ali.kaya@cornell.edu

Two of the major milestones in commissioning a beamline have been achieved on 24-ID-E at NE-CAT.  On August 9, 2024, x-rays were delivered by the APS through the Sector 24 front end. Using an ultrasensitive camera focused through a port of the monochromator, APS physicists detected the beam on the monochromator silicon crystals of both 24-ID-C and 24-ID-E. Though the focus was rough, NE-CAT was able to observe the beam.  After the September shutdown, Dr. Malcolm Capel was able to carefully steer the beam through the experimental hutches to the sample position over the next two months.

Read the story at WGN or watch to find one of the NE-CAT staff members.

NE-CAT is pleased to offer our Practical Crystallography Course June 3-6, 2024 at Meharry Medical College in Nashville, Tennessee.

The Advanced Photon Source has begun commissioning the new storage ring and as of Thursday, April 12, there is beam in the first few meters of the storage ring. To see the most recent updates by the Advanced Photon Source, check out the Upgrade website.