Publications

Found 14 results
Filters: Author is Schmidt, Aaron G  [Clear All Filters]
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Schmidt, A. G., Therkelsen, M. D., Stewart, S., Kepler, T. B., Liao, H. - X., M Moody, A., Haynes, B. F., and Harrison, S. C. (2015) Viral receptor-binding site antibodies with diverse germline origins. Cell. 161, 1026-1034
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Hauser, B. M., Sangesland, M., St Denis, K. J., Lam, E. C., Case, J. Brett, Windsor, I. W., Feldman, J., Caradonna, T. M., Kannegieter, T., Diamond, M. S., Balazs, A. B., Lingwood, D., and Schmidt, A. G. (2022) Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting. Cell Rep. 38, 110561
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Schmidt, A. G., Xu, H., Khan, A. R., O'Donnell, T., Khurana, S., King, L. R., Manischewitz, J., Golding, H., Suphaphiphat, P., Carfi, A., Settembre, E. C., Dormitzer, P. R., Kepler, T. B., Zhang, R., M Moody, A., Haynes, B. F., Liao, H. - X., Shaw, D. E., and Harrison, S. C. (2013) Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody. Proc Natl Acad Sci U S A. 110, 264-9
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McCarthy, K. R., Watanabe, A., Kuraoka, M., Do, K. T., McGee, C. E., Sempowski, G. D., Kepler, T. B., Schmidt, A. G., Kelsoe, G., and Harrison, S. C. (2018) Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires. Immunity. 48, 174-184.e9
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Raymond, D. D., Stewart, S. M., Lee, J., Ferdman, J., Bajic, G., Do, K. T., Ernandes, M. J., Suphaphiphat, P., Settembre, E. C., Dormitzer, P. R., Del Giudice, G., Finco, O., Kang, T. Hyun, Ippolito, G. C., Georgiou, G., Kepler, T. B., Haynes, B. F., M Moody, A., Liao, H. - X., Schmidt, A. G., and Harrison, S. C. (2016) Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain. Nat Med. 22, 1465-1469
Bajic, G., Maron, M. J., Adachi, Y., Onodera, T., McCarthy, K. R., McGee, C. E., Sempowski, G. D., Takahashi, Y., Kelsoe, G., Kuraoka, M., and Schmidt, A. G. (2019) Influenza Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope. Cell Host Microbe. 25, 827-835.e6
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Phillips, A. M., Maurer, D. P., Brooks, C., Dupic, T., Schmidt, A. G., and Desai, M. M. (2023) Hierarchical sequence-affinity landscapes shape the evolution of breadth in an anti-influenza receptor binding site antibody. Elife. 10.7554/eLife.83628
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McCarthy, K. R., Schmidt, A. G., Kirmaier, A., Wyand, A. L., Newman, R. M., and Johnson, W. E. (2013) Gain-of-sensitivity mutations in a Trim5-resistant primary isolate of pathogenic SIV identify two independent conserved determinants of Trim5α specificity.. PLoS Pathog. 9, e1003352
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Ray, R., Mohamed, F. Amokrane N., Maurer, D. P., Huang, J., Alpay, B. A., Ronsard, L., Xie, Z., Han, J., Fernandez-Quintero, M., Phan, Q. Anh, Ursin, R. L., Vu, M., Kirsch, K. H., Prum, T., Rosado, V. C., Bracamonte-Moreno, T., Okonkwo, V., Bals, J., McCarthy, C., Nair, U., Kanekiyo, M., Ward, A. B., Schmidt, A. G., Batista, F. D., and Lingwood, D. (2024) Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses. Immunity. 57, 1141-1159.e11
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Liu, Y., Pan, J., Jenni, S., Raymond, D. D., Caradonna, T., Do, K. T., Schmidt, A. G., Harrison, S. C., and Grigorieff, N. (2017) CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody-Antigen Interface. J Mol Biol. 429, 1829-1839
Raymond, D. D., Bajic, G., Ferdman, J., Suphaphiphat, P., Settembre, E. C., M Moody, A., Schmidt, A. G., and Harrison, S. C. (2018) Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody. Proc Natl Acad Sci U S A. 115, 168-173
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Watanabe, A., McCarthy, K. R., Kuraoka, M., Schmidt, A. G., Adachi, Y., Onodera, T., Tonouchi, K., Caradonna, T. M., Bajic, G., Song, S., McGee, C. E., Sempowski, G. D., Feng, F., Urick, P., Kepler, T. B., Takahashi, Y., Harrison, S. C., and Kelsoe, G. (2019) Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism. Cell. 177, 1124-1135.e16
Fera, D., Schmidt, A. G., Haynes, B. F., Gao, F., Liao, H. - X., Kepler, T. B., and Harrison, S. C. (2014) Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains. Proc Natl Acad Sci U S A. 111, 10275-80
McCarthy, K. R., Raymond, D. D., Do, K. T., Schmidt, A. G., and Harrison, S. C. (2019) Affinity maturation in a human humoral response to influenza hemagglutinin. Proc Natl Acad Sci U S A. 10.1073/pnas.1915620116